ReviewApplied microbiology and biotechnology2015
An updated view on horseradish peroxidases: recombinant production and biotechnological applications.
Review in Applied microbiology and biotechnology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
73 citing papers in PubMed.
- Engineered indoleamine 2,3-dioxygenase variant: Oxidative activation of prodrug indole-3-acetic acid against cancer cells for targeted therapy.Molecular therapy. Oncology · 2026Article
- Directed Immobilization of Horseradish Peroxidase Using a Covalently Attached Competitive Inhibitor.Molecules (Basel, Switzerland) · 2026Article
- Electrochemical Dopamine Biosensor Based on Plant-Derived Peroxidase Immobilized on Titanate Nanowires.ACS omega · 2026Article
- Alkyne Nitro Tag Enables Stable and Efficient Protein Functionalization of Gold Nanoparticles.ACS applied materials & interfaces · 2026Article
- Vendor-specific HRP antibody conjugate differences lead to unexpected immunoassay reagent interactions.Bioanalysis · 2026Article
- Isolation and characterization of peroxidase from potato leaves Solanum tuberosum: Application in glucose diagnostic kit.Journal, genetic engineering & biotechnology · 2025Article
- Study on the High-Efficiency Expression of Horseradish Peroxidase inMolecules (Basel, Switzerland) · 2025Article
- A Simple and Cost-Efficient Method for the Production of Recombinant Horseradish Peroxidase in E. coli.Molecular biotechnology · 2025Article
- A Ratiometric Fluorescent Probe Based on Carbon Dots and Quantum Dots for Glucose Detection.Journal of fluorescence · 2025Article
- Iron oxide nanoparticles: biosynthesis, peroxidase-like activity, and biosafety.Applied microbiology and biotechnology · 2025Review
- Development of Broadly Applicable Reference EVs Expressing Horseradish Peroxidase.Journal of extracellular vesicles · 2025Article
- Cancer therapy with engineered nanozymes: from molecular design to tumour-responsive catalysis.Nanomedicine (London, England) · 2025Review
- Research strategies of the N-peptide fusion inhibitor: a promising direction for discovering novel antivirals.Journal of virology · 2025Review
- AFM-Based Monitoring of Enzymatic Activity of Individual Molecules of Cytochrome CYP102A1.Biosensors · 2025Article
- Stabilization of the Ferryl═Oxoheme Form ofJournal of the American Chemical Society · 2025Article
- Incubation of Horseradish Peroxidase near 50 Hz AC Equipment Promotes Its Disaggregation and Enzymatic Activity.Micromachines · 2025Article
- Metabolic engineering of yeast to efficiently synthesize heme and hemoproteins: recent advance and prospects.FEMS yeast research · 2025Review
- Efficient and highly amplified imaging of nucleic acid targets in cellular and histopathological samples with pSABER.Nature methods · 2025Article
- Exploring Chemical Spaces in the Billion Range: Is Docking a Computational Alternative to DNA-Encoded Libraries?Journal of chemical information and modeling · 2024Article
- A Cost-Effective Hemin-Based Artificial Enzyme Allows for Practical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Horseradish peroxidase has been the subject of scientific research for centuries. It has been used exhaustively as reporter enzyme in diagnostics and histochemistry and still plays a major role in these applications. Numerous studies have been conducted on the role of horseradish peroxidase in the plant and its catalytic mechanism. However, little progress has been made in its recombinant production. Until now, commercial preparations of horseradish peroxidase are still isolated from plant roots. These preparations are commonly mixtures of various isoenzymes of which only a small fraction has been described so far. The composition of isoenzymes in these mixed isolates is subjected to uncontrollable environmental conditions. Nowadays, horseradish peroxidase regains interest due to its broad applicability in the fields of medicine, life sciences, and biotechnology in cancer therapy, biosensor systems, bioremediation, and biocatalysis. These medically and commercially relevant applications, the recent discovery of new natural isoenzymes with different biochemical properties, as well as the challenges in recombinant production render this enzyme particularly interesting for future biotechnological solutions. Therefore, we reviewed previous studies as well as current developments with biotechnological emphasis on new applications and the major remaining biotechnological challenge-the efficient recombinant production of horseradish peroxidase enzymes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.