Evidence map›Paper›PMID 25575099›Full record

ArticleThe American journal of case reports2015

Membranoproliferative glomerulonephritis due to visceral leishmaniasis in an HIV patient.

Ricardo Enríquez, Ana Esther Sirvent, Sergio Padilla, Paula Toro, María Sánchez, Isabel Millán

Open access · hybridAbstract readCase Reports
In one paragraph

Article in The American journal of case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Anemia and lower limbs edemas in a patient with HIV infection.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2025
    Article
  3. Article
  4. Article
  5. Kidney complications of parasitic diseases.Nature reviews. Nephrology · 2022
    Review
  6. A rare cause of postinfectious glomerulonephritis: Answers.Pediatric nephrology (Berlin, Germany) · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Visceral Leishmaniasis and Glomerulonephritis: A Case Report.Saudi journal of medicine & medical sciences
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ricardo EnríquezNephrology Section, Hospital General Universitario de Elche, Elche, Spain.
Ana Esther SirventNephrology Section, Hospital General Universitario de Elche, Elche, Spain.
Sergio PadillaInfectious Diseases Unit, Hospital General Universitario de Elche, Elche, Spain.
Paula ToroPathology Section, Hospital General Universitario de Elche, Elche, Spain.
María SánchezNephrology Section, Hospital General Universitario de Elche, Elche, Spain.
Isabel MillánNephrology Section, Hospital General Universitario de Elche, Elche, Spain.
Hospital General Universitario de Elche · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVisceral leishmaniasis is an important opportunistic disease in HIV-positive patients. The information available on the effects of such co-infection in the kidney is limited. We describe a patient with HIV/leishmania coinfection who developed nephrotic syndrome and membranoproliferative glomerulonephritis. As far as we know, only 2 cases of this nephropathy in HIV/leishmania coinfection have been reported. CASE REPORT: A 47-year-old man developed nephrotic syndrome. He had been diagnosed with HIV infection and visceral leishmaniasis and was treated with antiretroviral therapy, antimonial compounds, liposomal amphotericin B and miltefosine, but the leishmania followed a relapsing course. Renal biopsy disclosed membranoproliferative glomerulonephritis and leishmania amastigotes were seen within glomerular capillary lumens. He was given miltefosine and liposomal amphotericin B but the leishmaniasis persisted. Stage 3B chronic renal disease and nephrotic range proteinuria tend to become stable by 15-month follow-up.

conclusionsOur case illustrated some aspects of leishmaniasis in HIV patients: its relapsing course, the difficulties in therapy, and the renal involvement.

Indexed as

HIVAIDS-Related Opportunistic InfectionsBiopsyDiagnosis, DifferentialGlomerulonephritis, MembranoproliferativeHumansKidney GlomerulusLeishmaniasis, VisceralMaleMiddle Aged

Identifiers

PMID25575099
PMCPMC4299756
OpenAlexW2094161235

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.