ArticleBiomedical optics express2014
Quantifying the vascular response to ischemia with speckle variance optical coherence tomography.
Article in Biomedical optics express, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Aging and intraocular pressure homeostasis in mice.Aging cell · 2024Article
- Growing Trend to Adopt Speckle Variance Optical Coherence Tomography for Biological Tissue Assessments in Pre-Clinical Applications.Micromachines · 2024Review
- Binary dose level classification of tumour microvascular response to radiotherapy using artificial intelligence analysis of optical coherence tomography images.Scientific reports · 2022Article
- Influence of Substrate Stiffness on Barrier Function in an iPSC-DerivedCellular and molecular bioengineering · 2022Article
- Optical coherence microangiography of the mouse kidney for diagnosis of circulatory disorders.Biomedical optics express · 2021Article
- Article
- Integral role for lysyl oxidase-like-1 in conventional outflow tissue function and behavior.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020Article
- Optical coherence tomography angiography for noninvasive evaluation of angiogenesis in a limb ischemia mouse model.Scientific reports · 2019Article
- In vivo measurement of trabecular meshwork stiffness in a corticosteroid-induced ocular hypertensive mouse model.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Assessment of microvasculature flow state with a high speed all-optic dual-modal system of optical coherence tomography and photoacoustic imaging.Biomedical optics express · 2018Article
- Evaluating the effects of maternal alcohol consumption on murine fetal brain vasculature using optical coherence tomography.Journal of biophotonics · 2018Article
- Drug-Free ROS Sponge Polymeric Microspheres Reduce Tissue Damage from Ischemic and Mechanical Injury.ACS biomaterials science & engineering · 2018Article
- Noninvasive assessment of cutaneous alterations in mice exposed to whole body gamma irradiation using optical imaging techniques.Lasers in medical science · 2017Article
- Copolymer-Mediated Cell Aggregation Promotes a Proangiogenic Stem Cell Phenotype In Vitro and In Vivo.Advanced healthcare materials · 2016Article
- Visualization of conventional outflow tissue responses to netarsudil in living mouse eyes.European journal of pharmacology · 2016Article
- ROS-responsive microspheres for on demand antioxidant therapy in a model of diabetic peripheral arterial disease.Biomaterials · 2015Article
Corrections and comments
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Authors and funding
5 authors.
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Abstract
Longitudinal monitoring techniques for preclinical models of vascular remodeling are critical to the development of new therapies for pathological conditions such as ischemia and cancer. In models of skeletal muscle ischemia in particular, there is a lack of quantitative, non-invasive and long term assessment of vessel morphology. Here, we have applied speckle variance optical coherence tomography (OCT) methods to quantitatively assess vascular remodeling and growth in a mouse model of peripheral arterial disease. This approach was validated on two different mouse strains known to have disparate rates and abilities of recovering following induction of hind limb ischemia. These results establish the potential for speckle variance OCT as a tool for quantitative, preclinical screening of pro- and anti-angiogenic therapies.
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