Evidence map›Paper›PMID 25574423›Full record

ArticleBiomedical optics express2014

Trace cancer biomarker quantification using polystyrene-functionalized gold nanorods.

Jian Wu, Wei Li, Ghazal Hajisalem, Ariella Lukach, Eugenia Kumacheva, Fraser Hof, Reuven Gordon

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. High Stability Au NPs: From Design to Application in Nanomedicine.International journal of nanomedicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jian WuDepartment of Electrical Engineering, University of Victoria, Victoria, British Columbia V8W 2Y2, Canada.
Wei LiDepartment of Chemistry, University of Victoria, Victoria, British Columbia V8W 3V6, Canada.
Ghazal HajisalemDepartment of Electrical Engineering, University of Victoria, Victoria, British Columbia V8W 2Y2, Canada.
Ariella LukachDepartment of Chemistry, University of Toronto, 80 Saint George Street, Toronto, Ontario M5S 3H6, Canada.
Eugenia KumachevaDepartment of Chemistry, University of Toronto, 80 Saint George Street, Toronto, Ontario M5S 3H6, Canada.
Fraser HofDepartment of Chemistry, University of Victoria, Victoria, British Columbia V8W 3V6, Canada.
Reuven GordonDepartment of Electrical Engineering, University of Victoria, Victoria, British Columbia V8W 2Y2, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We demonstrate the application of polystyrene-functionalized gold nanorods (AuNRs) as a platform for surface enhanced Raman scattering (SERS) quantification of the exogenous cancer biomarker Acetyl Amantadine (AcAm). We utilize the hydrophobicity of the polystyrene attached to the AuNR surface to capture the hydrophobic AcAm from solution, followed by drying and detection using SERS. We achieve a detection limit of 16 ng/mL using this platform. This result shows clinical potential for low-cost early cancer detection.

Indexed as

(240.6680) Surface plasmons(240.6695) Surface-enhanced Raman scattering(280.4788) Optical sensing and sensors

Identifiers

PMID25574423
PMCPMC4285590

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.