Evidence map›Paper›PMID 25574212›Full record

ArticleExperimental and therapeutic medicine2015

Protective effect of the combinations of glycyrrhizic, ferulic and cinnamic acid pretreatment on myocardial ischemia-reperfusion injury in rats.

Yuqin Gao, Jiping Hao, Hongkao Zhang, Guoqiang Qian, Renwang Jiang, Jing Hu, Jianing Wang, Zhang Lei, Guoping Zhao

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Ferulic Acid against Cyclophosphamide-Induced Heart Toxicity in Mice by Inhibiting NF-κB Pathway.Evidence-based complementary and alternative medicine : eCAM · 2016
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Yuqin GaoDepartment of Cardiology, Ninth Affiliated Hospital of the Medical College of Xi'an Jiaotong University and Railway Central Hospital of Xi'an, Xi'an, Shanxi 710054, P.R. China ; College of Medicine, Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Jiping HaoDepartment of Cardiology, Ninth Affiliated Hospital of the Medical College of Xi'an Jiaotong University and Railway Central Hospital of Xi'an, Xi'an, Shanxi 710054, P.R. China.
Hongkao ZhangDepartment of Nursing Science, Huanghuai University, Zhumadian, Henan 463000, P.R. China.
Guoqiang QianCollege of Pharmacy, Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Renwang JiangDepartment of Cardiology, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China.
Jing HuCollege of Medicine, Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Jianing WangDepartment of Cardiology, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China.
Zhang LeiDepartment of Cardiology, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China.
Guoping ZhaoCollege of Medicine, Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Hubei University of Medicine · CNJinan University · CNXi'an Jiaotong University · CNHuanghuai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to find an effective drug cocktail pretreatment to protect myocardial tissue of the heart from ischemia-reperfusion (I/R) injury. The mechanisms underlying the effects of the drug cocktail were subsequently explored in order to expand the application of Dang-gui-si-ni-tang (DGSN), a Traditional Chinese Medicine. The active components of DGSN in the serum following oral administration were investigated using high-performance liquid chromatography. The activity of superoxide dismutase (SOD) and malondialdehyde (MDA) levels were then analyzed to show the effect of the active components in the treatment of myocardial I/R injury. An

Indexed as

cinnamic acidferulic acidglycyrrhizic acidischemia-reperfusion cocktail

Identifiers

PMID25574212
PMCPMC4280987
OpenAlexW1987624824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.