Evidence map›Paper›PMID 25574176›Full record

ReviewJournal of environmental and public health2014

The shared pathoetiological effects of particulate air pollution and the social environment on fetal-placental development.

Anders C Erickson, Laura Arbour

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of environmental and public health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02786420 (Imaging Innovations for Placental Assessment in Response to Environmental Pollution), which is not on this map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02786420 completednot on this mapstarted 2015, after this paper: background citation

Imaging Innovations for Placental Assessment in Response to Environmental Pollution

TypeobservationalSponsorUniversity of California, Los AngelesRan2015 to 2020Enrolled199ConditionsPlacental Disease
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Associations among PMEnvironmental research communications · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Prenatal PMToxics · 2024
    Review
  10. Review
  11. Article
  12. Article
  13. Benzene and NOInternational journal of environmental research and public health · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Exposome and Social Vulnerability: An Overview of the Literature Review.International journal of environmental research and public health · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anders C EricksonDivision of Medical Sciences, University of Victoria, Medical Science Building, Room 104, P.O. Box 1700 STN CSC, Victoria, BC, Canada V8W 2Y2.ORCID 0000-0003-3306-5364
Laura ArbourDivision of Medical Sciences, University of Victoria, Medical Science Building, Room 104, P.O. Box 1700 STN CSC, Victoria, BC, Canada V8W 2Y2 ; Department of Medical Genetics, University of British Columbia, C201, 4500 Oak Street Vancouver, BC, Canada V6H 3N1.ORCID 0000-0002-9589-0880

Funding

Canadian Institutes of Health Research IPH-98849
6 · The paper itself

Abstract

Exposure to particulate air pollution and socioeconomic risk factors are shown to be independently associated with adverse pregnancy outcomes; however, their confounding relationship is an epidemiological challenge that requires understanding of their shared etiologic pathways affecting fetal-placental development. The purpose of this paper is to explore the etiological mechanisms associated with exposure to particulate air pollution in contributing to adverse pregnancy outcomes and how these mechanisms intersect with those related to socioeconomic status. Here we review the role of oxidative stress, inflammation and endocrine modification in the pathoetiology of deficient deep placentation and detail how the physical and social environments can act alone and collectively to mediate the established pathology linked to a spectrum of adverse pregnancy outcomes. We review the experimental and epidemiological literature showing that diet/nutrition, smoking, and psychosocial stress share similar pathways with that of particulate air pollution exposure to potentially exasperate the negative effects of either insult alone. Therefore, socially patterned risk factors often treated as nuisance parameters should be explored as potential effect modifiers that may operate at multiple levels of social geography. The degree to which deleterious exposures can be ameliorated or exacerbated via community-level social and environmental characteristics needs further exploration.

Indexed as

Environmental ExposurePregnancy OutcomeSocial ClassAir PollutantsFemaleHumansParticulate MatterPregnancyPrenatal Exposure Delayed EffectsSocial EnvironmentAir PollutantsParticulate Matter

Identifiers

PMID25574176
PMCPMC4276595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.