Evidence map›Paper›PMID 25574087›Full record

ReviewWorld journal of gastroenterology2015

Pharmacological therapy used in the elimination of Helicobacter pylori infection: a review.

Ariolana A Dos Santos, Adriana A Carvalho

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Article
  3. Prevalence of cagA, cagM, vacA and oipA genes in isolates of Helicobacter pylori obtained from hospital patients in Northeast Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  4. GC-MS Profiling, Anti-Plants (Basel, Switzerland) · 2022
    Article
  5. Bacteriophages ofFrontiers in microbiology · 2020
    Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Antibiotic treatment for Helicobacter pylori: Is the end coming?World journal of gastrointestinal pharmacology and therapeutics · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ariolana A Dos SantosAriolana A dos Santos, Adriana A Carvalho, Department of Pharmacy, Federal University of Sergipe, Campus Lagarto, 49400-00 Lagarto, Sergipe, Brazil.
Adriana A CarvalhoAriolana A dos Santos, Adriana A Carvalho, Department of Pharmacy, Federal University of Sergipe, Campus Lagarto, 49400-00 Lagarto, Sergipe, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The optimal therapy for Helicobacter pylori (H. pylori) infection should combine a high cure rate and a short treatment duration with a favorable side-effect profile and should maintain a low cost. Several strategies have been proposed to increase the H. pylori eradication rate, including the extension of the treatment duration to 14 d, the use of a four-drug regimen (quadruple, sequential, and concomitant treatments), and the use of novel antibiotics, such as levofloxacin. However, triple therapy remains the most widely accepted first-line treatment regimen in Brazil and the United States and throughout Europe. Because this therapy is limited by resistance to clarithromycin, other therapeutic regimens have been investigated worldwide. This review describes the current literature involving studies directly comparing these different therapies and their efficacies.

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialDrug Therapy, CombinationHelicobacter InfectionsHelicobacter pyloriHumansProton Pump InhibitorsTreatment OutcomeAnti-Bacterial AgentsProton Pump InhibitorsClarithromycin resistantHelicobacter pyloriPeptic ulcersTreatmentTriple therapy

Identifiers

PMID25574087
PMCPMC4284330

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.