Evidence map›Paper›PMID 25572620›Full record

Trial reportPreventive medicine2015

Efficacy of a tobacco quitline among adult cancer survivors.

Robert C Klesges, Rebecca A Krukowski, James L Klosky, Wei Liu, Deo Kumar Srivastava, James M Boyett, Jennifer Q Lanctot, Melissa M Hudson, Charla Folsom, Harry Lando and 1 more

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Preventive medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00827866 (Efficacy of Tobacco Quitline for Cancer Survivors), which is not on this map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00827866 nacompletednot on this map

Efficacy of Tobacco Quitline for Cancer Survivors

TypeinterventionalSponsorSt. Jude Children's Research HospitalRan2008 to 2013Enrolled946ConditionsSmoking CessationArmsCounselor-Initiated Tobacco Quit Line, Self-Paced Tobacco Quit Line
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Psycho-oncology · 2020
    Pooled it
  2. Pooled it
  3. Telephone counselling for smoking cessation.The Cochrane database of systematic reviews · 2019
    Pooled it
  4. A randomized controlled trial to reduce post-cessation weight gain.International journal of obesity (2005) · 2023
    Trial
  5. Trial
  6. Review
  7. Associations between Cigarette Smoking and Health-Related Quality of Life in Adult Survivors of Adolescent and Young Adult Cancer.Journal of cancer education : the official journal of the American Association for Cancer Education · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Treating Nicotine Dependence and Preventing Smoking Relapse in Cancer Patients.Expert review of quality of life in cancer care · 2017
    Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Robert C KlesgesDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, USA; The Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN, USA. Electronic address: rklesges@uthsc.edu.
Rebecca A KrukowskiThe Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
James L KloskyDepartment of Psychology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Wei LiuDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA.
Deo Kumar SrivastavaDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA.
James M BoyettDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA.
Jennifer Q LanctotDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, USA.
Melissa M HudsonDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Charla FolsomDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, USA.
Harry LandoDivision of Epidemiology & Community Health, University of Minnesota, Minneapolis, MN, USA.
Leslie L RobisonDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, USA.
St. Jude Children's Research Hospital · USUniversity of Tennessee Health Science Center · USUniversity of Minnesota · US

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
Efficacy of a Tobacco Quit Line for Childhood Cancer SurvivorsR01CA127964 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI KLESGES, ROBERT C · 2008 to 2012
$3.1M
NCI NIH HHS CA127964NCI NIH HHS CA21765NCI NIH HHS P30 CA021765NCI NIH HHS R01 CA127964
6 · The paper itself

Abstract

objectiveThe purpose of the study (conducted 2010-2013) was to determine the efficacy of two common types of tobacco quitlines in adult cancer survivors who regularly smoked cigarettes.

methodAdult onset cancer survivors in Memphis, Tennessee (n=427, 67% female, 60% Caucasian) were randomized either to a Proactive (i.e., counselor-initiated calls) or Reactive (i.e., participant-initiated calls) quitline. Both conditions also received nicotine replacement therapy. The primary outcome was biochemically-verified (i.e., salivary cotinine) smoking cessation.

resultsWhile 12-month self-reported abstinence was consistent with other published studies of smoking cessation (22% and 26% point prevalence abstinence for Proactive and Reactive conditions, respectively), 48% of participants who were tested for cotinine failed biochemical verification, indicating a considerable falsification of self-reported cessation. Adjusted cessation rates were less than 5% in both intervention conditions.

conclusionOur results are consistent with other studies indicating that traditional smoking cessation interventions are ineffective among cancer survivors. Moreover, self-reports of cessation were unreliable in cancer survivors participating in a quitline intervention, indicating that future studies should include biochemical verification. Given the importance of smoking cessation among cancer survivors and low cessation rates in the current study, it may be necessary to design alternative interventions for this population. ClinicalTrials.gov identifier: NCT00827866.

Indexed as

HotlinesAdultFemaleHumansMaleNeoplasmsProgram EvaluationSmokingSmoking CessationSurvivorsTennesseeTobacco Use Cessation DevicesAdultsCancerIntervention studiesSmoking cessationSurvivors

Identifiers

PMID25572620
PMCPMC4355239
OpenAlexW2013323574

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.