Observational studyJournal of the American College of Cardiology2015
Cost-effectiveness of revascularization strategies: the ASCERT study.
Observational study in Journal of the American College of Cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06034405 (Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Big Data in cardiac surgery: real world and perspectives.Journal of cardiothoracic surgery · 2022Pooled it
- Cost-Effectiveness of Icosapent Ethyl in REDUCE-IT USA: Results From Patients Randomized in the United States.Journal of the American Heart Association · 2024Trial
- Resource Use Following Revascularization for Multivessel Coronary Artery Disease.Journal of the American Heart Association · 2026Article
- Prediction of post-PCI angina risk using machine learning-based magnetocardiography model.Frontiers in cardiovascular medicine · 2026Article
- Cost-Utility Analysis of Different Treatment Modalities in Patients Undergoing Percutaneous Coronary Intervention: Thai PCI Registry.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025Article
- Etiology and clinical outcomes in patients undergoing coronary artery bypass grafting in the second decade of life.Indian journal of thoracic and cardiovascular surgery · 2025Article
- ChatGPT's Role in Coronary Artery Bypass Graft Information: A Critical Assessment.Sisli Etfal Hastanesi tip bulteni · 2025Article
- Cost-effectiveness of Icosapent Ethyl for High-risk Patients With Hypertriglyceridemia Despite Statin Treatment.JAMA network open · 2022Article
- Estimating Systolic Blood Pressure Intervention Trial Participant Posttrial Survival Using Pooled Epidemiologic Cohort Data.Journal of the American Heart Association · 2021Article
- Machine-Learning Techniques for Feature Selection and Prediction of Mortality in Elderly CABG Patients.Healthcare (Basel, Switzerland) · 2021Article
- Cost-Effectiveness of Coronary Artery Bypass Grafting and Percutaneous Coronary Intervention in Patients With Chronic Kidney Disease and Acute Coronary Syndromes in the US Medicare Program.Journal of the American Heart Association · 2021Article
- Treatment selection and medication adherence for stable angina: The role of area-based health literacy.Journal of evaluation in clinical practice · 2020Article
- Clinical outcomes of prolonged dual antiplatelet therapy after coronary drug-eluting stent implantation in dialysis patients.Clinical kidney journal · 2020Article
- Patient-Clinician Decision Making for Stable Angina: The Role of Health Literacy.EGEMS (Washington, DC) · 2019Article
- Role of Big Data in Cardiovascular Research.Journal of the American Heart Association · 2019Review
- Cognitive Change After Cardiac Surgery Versus Cardiac Catheterization: A Population-Based Study.The Annals of thoracic surgery · 2019Article
- Burden of Coronary Artery Disease and Peripheral Artery Disease: A Literature Review.Cardiovascular therapeutics · 2019Review
- The Cost Effectiveness of Single-Patient-Use Electrocardiograph Cable and Lead Systems in Monitoring for Coronary Artery Bypass Graft Surgery.Frontiers in cardiovascular medicine · 2019Article
- Cost-effectiveness analysis in cardiac surgery: A review of its concepts and methodologies.The Journal of thoracic and cardiovascular surgery · 2018Review
- Advances in Cardiovascular Care: How to Stimulate Innovation While Controlling Cost.JACC. Basic to translational science · 2018Review
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
backgroundASCERT (American College of Cardiology Foundation and the Society of Thoracic Surgeons Collaboration on the Comparative Effectiveness of Revascularization Strategies) was a large observational study designed to compare the long-term effectiveness of coronary artery bypass graft (CABG) and percutaneous coronary intervention (PCI) to treat coronary artery disease (CAD) over 4 to 5 years.
objectivesThis study examined the cost-effectiveness of CABG versus PCI for stable ischemic heart disease.
methodsThe Society of Thoracic Surgeons and American College of Cardiology Foundation databases were linked to the Centers for Medicare and Medicaid Services claims data. Costs for the index and observation period (2004 to 2008) hospitalizations were assessed by diagnosis-related group Medicare reimbursement rates; costs beyond the observation period were estimated from average Medicare participant per capita expenditure. Effectiveness was measured via mortality and life-expectancy data. Cost and effectiveness comparisons were adjusted using propensity score matching with the incremental cost-effectiveness ratio expressed as cost per quality-adjusted life-year gained.
resultsCABG patients (n = 86,244) and PCI patients (n = 103,549) were at least 65 years old with 2- or 3-vessel coronary artery disease. Adjusted costs were higher for CABG for the index hospitalization, study period, and lifetime by $10,670, $8,145, and $11,575, respectively. Patients undergoing CABG gained an adjusted average of 0.2525 and 0.3801 life-years relative to PCI over the observation period and lifetime, respectively. The life-time incremental cost-effectiveness ratio of CABG compared to PCI was $30,454/QALY gained.
conclusionsOver a period of 4 years or longer, patients undergoing CABG had better outcomes but at higher costs than those undergoing PCI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.