ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2015
Risk of osteoporotic fractures following stroke in older persons.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- The effect of stroke on the bone mineral density: A systematic review and meta-analysis.The journal of nutrition, health & aging · 2024Pooled it
- Stroke increases the risk of hip fracture: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016Pooled it
- Risk of hip fracture following stroke, a meta-analysis of 13 cohort studies.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016Pooled it
- Pioglitazone and Risk for Bone Fracture: Safety Data From a Randomized Clinical Trial.The Journal of clinical endocrinology and metabolism · 2017Trial
- Discordance Between Spine-Hip and Paretic-Nonparetic Hip Bone Mineral Density in Hemiplegic Stroke Patients: A Multicenter Retrospective Study.Annals of rehabilitation medicine · 2024Article
- The pathogenesis of post-stroke osteoporosis and the role oxidative stress plays in its development.Frontiers in medicine · 2023Review
- Interleukin-13 Affects the Recovery Processes in a Mouse Model of Hemorrhagic Stroke with Bilateral Tibial Fracture.Molecular neurobiology · 2022Article
- Clinical Correlation Analysis of Complications in Elderly Patients with Sequelae of Stroke with Different Barthel Index in Tianjin Emergency Department.BioMed research international · 2021Article
- Association between post-stroke disability and 5-year hip-fracture risk: The Women's Health Initiative.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2020Observational
- A Study of Risk Factors for Early-Onset Adjacent Vertebral Fractures After Kyphoplasty.Global spine journal · 2020Article
- Osteoporotic hip fracture prediction from risk factors available in administrative claims data - A machine learning approach.PloS one · 2020Observational
- Epidemiology of hip fractures : Systematic literature review of German data and an overview of the international literature.Zeitschrift fur Gerontologie und Geriatrie · 2019Review
- Non-vitamin K Antagonist Oral Anticoagulants vs. Warfarin at Risk of Fractures: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Frontiers in pharmacology · 2018Article
- The Importance of Assessing Nutritional Status to Ensure Optimal Recovery during the Chronic Phase of Stroke.Stroke research and treatment · 2018Review
- Impact and risk factors of post-stroke bone fracture.World journal of experimental medicine · 2016Article
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledThe aim of this study was to explore the increased risk of stroke survivors to different sustained osteoporotic fractures. We used hospital data and data on functional impairment. We found a higher risk in stroke survivors without functional impairment with the risk higher for lower than for upper extremity fractures.
introductionStroke survivors are at high risk of osteoporotic fractures due to frequent falls and an increased risk to develop osteoporosis. Data on their relative risk to sustain other than hip fractures is limited. Furthermore, the role of severe functional impairment on their fracture risk has not been considered yet. The aim of this study was to determine the relative risk of stroke survivors to sustain different osteoporotic fractures with regard to the presence of severe functional impairment.
methodsData from 2004 to 2009 of more than 1.2 million individuals aged 65 years or older and insured at a large German health insurance company were used for the analyses. Incident stroke and fractures were obtained from hospital diagnoses. Analyses were stratified by gender and information on severe functional impairment. Persons without preceding incident stroke were used as the reference group. Multistate models were used to estimate hazard ratios.
resultsStroke survivors had a higher risk for fractures. However, a strong effect modification by functional impairment was apparent. Stroke survivors with functional impairment had no significantly increased risk for any fractures site compared to the corresponding reference group with functional impairment. In contrast, stroke survivors without functional impairment had a clearly and significantly increased fracture risk for most fracture sites. In these persons, the relative fracture risk for fractures of the lower extremities was higher than for fractures of the upper extremities.
conclusionTo evaluate the relative risk of stroke survivors for osteoporotic fractures, functional status appears to be a relevant parameter.
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