ReviewBritish dental journal2015
Periodontitis: a potential risk factor for Alzheimer's disease.
Review in British dental journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Is Periodontitis Associated with Age-Related Cognitive Impairment? The Systematic Review, Confounders Assessment and Meta-Analysis of Clinical Studies.International journal of molecular sciences · 2022Pooled it
- Evidence and Therapeutic Perspectives in the Relationship between the Oral Microbiome and Alzheimer's Disease: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Article
- Exploring the gut-brain axis: dietary influences on Alzheimer's disease pathogenesis.Frontiers in microbiomes · 2026Review
- Systemic inflammation as a central player in the initiation and development of Alzheimer's disease.Immunity & ageing : I & A · 2025Review
- Phospho-tau 181 is enhanced in saliva and plasma of edentulous patients: a first sign of dementia?Frontiers in oral health · 2025Article
- Global, regional, and national burden of periodontal diseases from 1990 to 2021 and predictions to 2040: an analysis of the global burden of disease study 2021.Frontiers in oral health · 2025Article
- Human oral microbiome and its influence on mental health and brain disorders.AIMS microbiology · 2025Review
- Oral Microbiome Stamp in Alzheimer's Disease.Pathogens (Basel, Switzerland) · 2024Article
- Association between periodontitis treatment and dementia in Taiwanese adults.BMC oral health · 2023Article
- Review
- Guided Bone Regeneration in a Periodontally Compromised Individual with Autogenous Tooth Bone Graft: A Radiomics Analysis.Journal of functional biomaterials · 2023Article
- Helicobacter pylori infection in the stomach induces neuroinflammation: the potential roles of bacterial outer membrane vesicles in an animal model of Alzheimer's disease.Inflammation and regeneration · 2022Review
- Multi-Omics Analysis Reveals the Systematic Relationship Between Oral Homeostasis and Chronic Sleep Deprivation in Rats.Frontiers in immunology · 2022Article
- Gut Microbiota, Probiotic Interventions, and Cognitive Function in the Elderly: A Review of Current Knowledge.Nutrients · 2021Review
- Dental Care Utilization of Hospitalized Persons Living with HIV and Substance Use.Journal of community health · 2021Article
- Factors Influencing Oral Health-Related Quality of Life in Older Adults in Rural Areas: Oral Dryness and Oral Health Knowledge and Behavior.International journal of environmental research and public health · 2021Article
- CanJournal of Alzheimer's disease reports · 2021Article
- Article
- Downregulation of lncRNA ANRIL Inhibits Osteogenic Differentiation of Periodontal Ligament Cells via Sponging miR-7 through NF-Analytical cellular pathology (Amsterdam) · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The role of periodontitis as a risk factor for multiple systemic diseases is widely accepted and there is growing evidence of an association between periodontitis and sporadic late onset Alzheimer's disease (SLOAD). Recent epidemiologic, microbiologic and inflammatory findings strengthen this association, indicating that periodontal pathogens are possible contributors to neural inflammation and SLOAD. The aim of this article is to present contemporary evidence of this association.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.