ArticleAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference2014
A structural framework for interpretation of four-electrode microimpedance spectra in cardiac tissue.
Article in Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- A modified approach to determine the six cardiac bidomain conductivities.Computers in biology and medicine · 2021Article
- Extracellular sodium dependence of the conduction velocity-calcium relationship: evidence of ephaptic self-attenuation.American journal of physiology. Heart and circulatory physiology · 2016Article
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2 authors.
Funding
Abstract
Renewed interest in the four-electrode method for identification of passive electrical properties in cardiac tissue has been sparked by a recognition that measurements made with sensors in close proximity are frequency dependent. Therefore, resolution of four-electrode microimpedance spectra (4EMS) may provide an opportunity for routine identification of passive electrical properties for the interstitial and intracellular compartments using only interstitial access. The present study documents a structural framework in which the tissue resistivity (ρt) and reactivity (xt) that comprise spectra are computed using interstitial and intracellular microimpedance distributions that account for differences in compartment size, anisotropic electrical properties in each compartment and electrode separations. We used this framework to consider 4EMS development with relatively wide (d=1 mm) and fine (d=250 μm) electrode separations and sensors oriented along myocyte axes, across myocyte axes and intermediate between those axes.
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