ArticleSensors (Basel, Switzerland)2015
Hyper, a hydrogen peroxide sensor, indicates the sensitivity of the Arabidopsis root elongation zone to aluminum treatment.
Article in Sensors (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 74 citations in OpenAlex.
- Isolation and characterization of Avena sativa catalase 1 gene (AsCAT1) with potential role in plant response to abiotic stress conditions.Protoplasma · 2026Article
- Genome-Wide Association Analyses Identify Hydrogen Peroxide-Responsive Loci in Wheat Diversity.Plant direct · 2025Article
- CaBMC plant biology · 2025Article
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- Soybean Plants Exposed to Low Concentrations of Potassium Iodide Have Better Tolerance to Water Deficit through the Antioxidant Enzymatic System and Photosynthesis Modulation.Plants (Basel, Switzerland) · 2023Article
- HPlant, cell & environment · 2023Review
- Recent advances in fluorescent probes of peroxynitrite: Structural, strategies and biological applications.Theranostics · 2023Review
- Reactive oxygen species function as signaling molecules in controlling plant development and hormonal responses.Current opinion in plant biology · 2022Review
- Nanosensor Applications in Plant Science.Biosensors · 2022Review
- Mnsod1 promotes the development of Pleurotus ostreatus and enhances the tolerance of mycelia to heat stress.Microbial cell factories · 2022Article
- Interplay between Proline Metabolism and ROS in the Fine Tuning of Root-Meristem Size inPlants (Basel, Switzerland) · 2022Article
- Review
- Reactive Oxygen Species Link Gene Regulatory Networks DuringFrontiers in plant science · 2021Review
- In Vivo Imaging with Genetically Encoded Redox Biosensors.International journal of molecular sciences · 2020Review
- A Förster resonance energy transfer sensor for live-cell imaging of mitogen-activated protein kinase activity in Arabidopsis.The Plant journal : for cell and molecular biology · 2019Article
- HNano convergence · 2019Article
- A simple microfluidic device for live cell imaging of Arabidopsis cotyledons, leaves, and seedlings.BioTechniques · 2018Article
- Insights into the HyPer biosensor as molecular tool for monitoring cellular antioxidant capacity.Redox biology · 2018Article
- ROS Regulation of Polar Growth in Plant Cells.Plant physiology · 2016Review
- Hydrogen Peroxide Signaling in Plant Development and Abiotic Responses: Crosstalk with Nitric Oxide and Calcium.Frontiers in plant science · 2016Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Emerging evidence indicates that some reactive oxygen species (ROS), such as the superoxide anion radical and hydrogen peroxide (H2O2), are central regulators of plant responses to biotic and abiotic stresses. Thus, the cellular levels of ROS are thought to be tightly regulated by an efficient and elaborate pro- and antioxidant system that modulates the production and scavenging of ROS. Until recently, studies of ROS in plant cells have been limited to biochemical assays and the use of fluorescent probes; however, the irreversible oxidation of these fluorescent probes makes it impossible to visualize dynamic changes in ROS levels. In this work, we describe the use of Hyper, a recently developed live cell probe for H2O2 measurements in living cells, to monitor oxidative stress in Arabidopsis roots subjected to aluminum treatment. Hyper consists of a circularly permuted YFP (cpYFP) inserted into the regulatory domain of the Escherichia coli hydrogen peroxide-binding protein (OxyR), and is a H2O2-specific ratiometric, and therefore quantitative, probe that can be expressed in plant and animal cells. Now we demonstrate that H2O2 levels drop sharply in the elongation zone of roots treated with aluminum. This response could contribute to root growth arrest and provides evidence that H2O2 is involved in early Al sensing.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.