Evidence map›Paper›PMID 25569558›Full record

ArticlePloS one2015

Application of clinico-radiologic-pathologic diagnosis of diffuse parenchymal lung diseases in children in China.

Dan Xu, Zhimin Chen, Huizhong Chen, Rongyan Huang, Shunying Zhao, Xiuyun Liu, Chunju Zhou, Yun Peng, Xinyu Yuan, Jizhen Zou and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Dan XuDepartment of Pulmonology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhimin ChenDepartment of Pulmonology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Huizhong ChenDepartment of Respiratory Diseases, Children's Hospital, Affiliated to the Capital Institute of Pediatrics, Beijing, China.
Rongyan HuangDepartment of Respiratory Diseases, Children's Hospital, Affiliated to the Capital Institute of Pediatrics, Beijing, China.
Shunying ZhaoDepartment of Pediatric Internal Medicine, Beijing Children's Hospital Affiliated with Capital Medical University, Beijing, China.
Xiuyun LiuDepartment of Pediatric Internal Medicine, Beijing Children's Hospital Affiliated with Capital Medical University, Beijing, China.
Chunju ZhouDepartment of Pathology, Beijing Children's Hospital Affiliated with Capital Medical University, Beijing, China.
Yun PengDepartment of Radiology, Beijing Children's Hospital Affiliated with Capital Medical University, Beijing, China.
Xinyu YuanDepartment of Radiology, Children's Hospital, Affiliated to the Capital Institute of Pediatrics, Beijing, China.
Jizhen ZouDepartment of Pathology, C Children's Hospital, Affiliated to the Capital Institute of Pediatrics, Beijing, China.
Hailing ZhangDepartment of Respiratory Diseases, Yuying Children's Hospital Affiliated to Wenzhou Medical College, Wenzhou, China.
Deyu ZhaoDepartment of Respiratory Diseases, Nanjing Children's Hospital, Nanjing Medical University, Nanjing, China.
Enmei LiuRespiratory Center, Children's Hospital Affiliated with Chongqing Medical University, Chongqing, China.
Yuejie ZhengDepartment of Respiratory Diseases, Shenzhen Children's Hospital, Shenzhen, China.
Lili ZhongDepartment of Pediatrics, the First Affiliated Hospital of Hunan Normal University, Changsha, China.
Min LuDepartment of Pulmonology, Shanghai Children's Hospital Affiliated to Jiaotong University, Shanghai, China.
Jirong LuDepartment of Pediatrics, the First Hospital of Jilin University, Changchun, China.
Guangmin NongDepartment of Pediatrics, the First Affiliated Hospital, Guangxi Medical University, Nanning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledDiffuse parenchymal lung diseases in children (chDPLD) or interstitial lung diseases in children (chILD) represent a heterogeneous group of respiratory disorders that are mostly chronic and associated with high morbidity and mortality. However, the incidence of chDPLD is so low that most pediatricians lack sufficient knowledge of chDPLD, especially in China. Based on the clinico-radiologic-pathologic (CRP) diagnosis, we tried to describe (1) the characteristics of chDPLD and (2) the ratio of each constituent of chDPLD in China. Data were evaluated, including clinical, radiographic, and pathologic results from lung biopsies. We collected 25 cases of chDPLD, 18 boys and 7 girls with a median age of 6.0 years, from 16 hospitals in China. The most common manifestations included cough (n = 24), dyspnea (n = 21), and fever (n = 4). There were three cases of exposure-related interstitial lung disease (ILD), three cases of systemic disease-associated ILD, nineteen cases of alveolar structure disorder-associated ILD, and no cases of ILD specific to infancy. Non-specific interstitial pneumonia (n = 9) was the two largest groups.

conclusionNon-specific interstitial pneumonia is the main categories of chDPLD in China. Lung biopsy is always a crucial step in the final diagnosis. However, clinical and imaging studies should be carefully evaluated for their value in indicating a specific chDPLD.

Indexed as

AdolescentBronchoalveolar LavageChildChild, PreschoolChinaCoughDyspneaFemaleFeverHumansInfantLungLung Diseases, InterstitialMaleRespiratory Function TestsTomography, X-Ray Computed

Identifiers

PMID25569558
PMCPMC4287620

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.