Evidence map›Paper›PMID 25569221›Full record

ArticlePLoS computational biology2015

A RESTful API for accessing microbial community data for MG-RAST.

Andreas Wilke, Jared Bischof, Travis Harrison, Tom Brettin, Mark D'Souza, Wolfgang Gerlach, Hunter Matthews, Tobias Paczian, Jared Wilkening, Elizabeth M Glass and 2 more

Open access · goldAbstract read
In one paragraph

Article in PLoS computational biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 74 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. DIAMOND +  MEGAN Microbiome Analysis.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  9. Microbial Dark Matter: from Discovery to Applications.Genomics, proteomics & bioinformatics · 2022
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Symbiotic magnetic sensing: raising evidence and beyond.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Andreas WilkeMathematics and Computer Science Division, Argonne National Laboratory, Lemont, Illinois, United States of America; Computation Institute, University of Chicago, Chicago, Illinois, United States of America.
Jared BischofMathematics and Computer Science Division, Argonne National Laboratory, Lemont, Illinois, United States of America; Computation Institute, University of Chicago, Chicago, Illinois, United States of America.
Travis HarrisonMathematics and Computer Science Division, Argonne National Laboratory, Lemont, Illinois, United States of America; Computation Institute, University of Chicago, Chicago, Illinois, United States of America.
Tom BrettinMathematics and Computer Science Division, Argonne National Laboratory, Lemont, Illinois, United States of America.
Mark D'SouzaMathematics and Computer Science Division, Argonne National Laboratory, Lemont, Illinois, United States of America; Computation Institute, University of Chicago, Chicago, Illinois, United States of America.
Wolfgang GerlachMathematics and Computer Science Division, Argonne National Laboratory, Lemont, Illinois, United States of America; Computation Institute, University of Chicago, Chicago, Illinois, United States of America.
Hunter MatthewsMathematics and Computer Science Division, Argonne National Laboratory, Lemont, Illinois, United States of America; Computation Institute, University of Chicago, Chicago, Illinois, United States of America.
Tobias PaczianMathematics and Computer Science Division, Argonne National Laboratory, Lemont, Illinois, United States of America; Computation Institute, University of Chicago, Chicago, Illinois, United States of America.
Jared WilkeningMathematics and Computer Science Division, Argonne National Laboratory, Lemont, Illinois, United States of America; Computation Institute, University of Chicago, Chicago, Illinois, United States of America.
Elizabeth M GlassMathematics and Computer Science Division, Argonne National Laboratory, Lemont, Illinois, United States of America; Computation Institute, University of Chicago, Chicago, Illinois, United States of America.
Narayan DesaiMathematics and Computer Science Division, Argonne National Laboratory, Lemont, Illinois, United States of America; Computation Institute, University of Chicago, Chicago, Illinois, United States of America.
Folker MeyerMathematics and Computer Science Division, Argonne National Laboratory, Lemont, Illinois, United States of America; Computation Institute, University of Chicago, Chicago, Illinois, United States of America.
Argonne National Laboratory · USUniversity of Chicago · US

Funding

The Role of the Gut Microbiota in Ulcerative ColitisUH3DK083993 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHANG, EUGENE B, MEYER, FOLKER · 2010 to 2012
$8.2M
NIDDK NIH HHS UH3 DK083993
6 · The paper itself

Abstract

Metagenomic sequencing has produced significant amounts of data in recent years. For example, as of summer 2013, MG-RAST has been used to annotate over 110,000 data sets totaling over 43 Terabases. With metagenomic sequencing finding even wider adoption in the scientific community, the existing web-based analysis tools and infrastructure in MG-RAST provide limited capability for data retrieval and analysis, such as comparative analysis between multiple data sets. Moreover, although the system provides many analysis tools, it is not comprehensive. By opening MG-RAST up via a web services API (application programmers interface) we have greatly expanded access to MG-RAST data, as well as provided a mechanism for the use of third-party analysis tools with MG-RAST data. This RESTful API makes all data and data objects created by the MG-RAST pipeline accessible as JSON objects. As part of the DOE Systems Biology Knowledgebase project (KBase, http://kbase.us) we have implemented a web services API for MG-RAST. This API complements the existing MG-RAST web interface and constitutes the basis of KBase's microbial community capabilities. In addition, the API exposes a comprehensive collection of data to programmers. This API, which uses a RESTful (Representational State Transfer) implementation, is compatible with most programming environments and should be easy to use for end users and third parties. It provides comprehensive access to sequence data, quality control results, annotations, and many other data types. Where feasible, we have used standards to expose data and metadata. Code examples are provided in a number of languages both to show the versatility of the API and to provide a starting point for users. We present an API that exposes the data in MG-RAST for consumption by our users, greatly enhancing the utility of the MG-RAST service.

Indexed as

Database Management SystemsDatabases, GeneticUser-Computer InterfaceGenome, BacterialInternetMetagenomicsMolecular Sequence AnnotationSoftware

Identifiers

PMID25569221
PMCPMC4287624
OpenAlexW1997787178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.