Evidence map›Paper›PMID 25568644›Full record

ArticleFrontiers in biology2014

Regulation and function of stimulus-induced phosphorylation of MeCP2.

Hongda Li, Qiang Chang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. DNA Methylation and Adult Neurogenesis.Brain plasticity (Amsterdam, Netherlands) · 2017
    Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hongda LiWaisman Center, University of Wisconsin-Madison, Madison, WI 53705, USA ; Genetics Training Program, University of Wisconsin-Madison, Madison, WI 53705,USA.
Qiang ChangWaisman Center, University of Wisconsin-Madison, Madison, WI 53705, USA ; Genetics Training Program, University of Wisconsin-Madison, Madison, WI 53705,USA ; Department of Neurology, University of Wisconsin-Madison, Madison, WI 53705, USA.
University of Wisconsin–Madison · US

Funding

WISCONSIN CENTER ON MENTAL RETARDATION: CORE SUPPORTP30HD003352 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI MESSING, ALBEE · 1985 to 2015
$25.2M
In Vivo Function of Neuronal Activity-Induced MeCP2 phosphorylationR01HD064743 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI CHANG, QIANG · 2010 to 2021
$3.0M
Experience-Dependent Redeployment of MeCP2 Across the Mouse GenomeR21HD066560 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI CHANG, QIANG · 2010 to 2011
$401k
NICHD NIH HHS P30 HD003352NICHD NIH HHS R01 HD064743NICHD NIH HHS R21 HD066560
6 · The paper itself

Abstract

DNA methylation-dependent epigenetic regulation plays important roles in the development and function of the mammalian nervous system. MeCP2 is a key player in recognizing methylated DNA and interpreting the epigenetic information encoded in different DNA methylation patterns. Mutations in the

Indexed as

MeCP2phosphorylationRett syndrome

Identifiers

PMID25568644
PMCPMC4283599
OpenAlexW1998664576

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.