Evidence map›Paper›PMID 25568280›Full record

ArticleBioinformatics (Oxford, England)2015

The anisotropic network model web server at 2015 (ANM 2.0).

Eran Eyal, Gengkon Lum, Ivet Bahar

Open access · hybridAbstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 189 citations in OpenAlex.

  1. Article
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  3. Cryo-electron microscopy structure of a zinc uptake ABC transporter.bioRxiv : the preprint server for biology · 2025
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  6. Accurate identification and mechanistic evaluation of pathogenic missense variants withProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Article
  9. Article
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  11. Article
  12. Article
  13. Article
  14. Review
  15. The Onset of Molecule-Spanning Dynamics in Heat Shock Protein Hsp90.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Eran EyalCancer Research Institute, Sheba Medical Center, 2 Sheba Rd, Ramat Gan 52621, Israel and Department of Computational and System Biology, University of Pittsburgh, 3501 Fifth Ave, Pittsburgh, PA 15213, USA.
Gengkon LumCancer Research Institute, Sheba Medical Center, 2 Sheba Rd, Ramat Gan 52621, Israel and Department of Computational and System Biology, University of Pittsburgh, 3501 Fifth Ave, Pittsburgh, PA 15213, USA.
Ivet BaharCancer Research Institute, Sheba Medical Center, 2 Sheba Rd, Ramat Gan 52621, Israel and Department of Computational and System Biology, University of Pittsburgh, 3501 Fifth Ave, Pittsburgh, PA 15213, USA.
University of Pittsburgh · USSheba Medical Center · IL

Funding

Structural Dynamics of Biomolecular SystemsR01GM086238 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BAHAR, IVET · 2009 to 2012
$1.3M
Continued Development of Protein Dynamics Software ProDyR01GM099738 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BAHAR, IVET · 2012 to 2015
$1.1M
NIGMS NIH HHS 1R01GM099738NIGMS NIH HHS 5R01GM086238NIGMS NIH HHS R01 GM086238NIGMS NIH HHS R01 GM099738
6 · The paper itself

Abstract

summaryThe anisotropic network model (ANM) is one of the simplest yet powerful tools for exploring protein dynamics. Its main utility is to predict and visualize the collective motions of large complexes and assemblies near their equilibrium structures. The ANM server, introduced by us in 2006 helped making this tool more accessible to non-sophisticated users. We now provide a new version (ANM 2.0), which allows inclusion of nucleic acids and ligands in the network model and thus enables the investigation of the collective motions of protein-DNA/RNA and -ligand systems. The new version offers the flexibility of defining the system nodes and the interaction types and cutoffs. It also includes extensive improvements in hardware, software and graphical interfaces. AVAILABILITY AND IMPLEMENTATION: ANM 2.0 is available at http://anm.csb.pitt.edu CONTACT: eran.eyal@sheba.health.gov.il, eyal.eran@gmail.com.

Indexed as

SoftwareAnisotropyDNADNA-Binding ProteinsInternetLigandsMotionProtein ConformationProteinsRNARNA-Binding ProteinsDNADNA-Binding ProteinsLigandsProteinsRNARNA-Binding Proteins

Identifiers

PMID25568280
PMCPMC4410662
OpenAlexW2102725267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.