ArticleEvolutionary applications2011
Rapid selection against inbreeding in a wild population of a rare frog.
Article in Evolutionary applications, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- The relationship between genomic variation and genetic load: insights from small island populations.Heredity · 2026Article
- Importance of Spring Habitats for Amphibians: The Case of Estavelle Ecotones in the Classical Karst Region.Animals : an open access journal from MDPI · 2025Article
- Variations in Genetic Diversity of Invasive SpeciesAnimals : an open access journal from MDPI · 2024Article
- A centenary tale: population genetic insights into the introduction history of the oriental fire-bellied toad (Bombina orientalis) in Beijing.BMC ecology and evolution · 2022Article
- Annual climatic fluctuations and short-term genetic variation in the eastern spadefoot toad.Scientific reports · 2021Article
- Evolutionary principles guiding amphibian conservation.Evolutionary applications · 2020Review
- Article
- Temporal trends in genetic data and effective population size support efficacy of management practices in critically endangered dusky gopher frogs (Lithobates sevosus).Ecology and evolution · 2016Article
- High genetic diversity of common toad (Bufo bufo) populations under strong natural fragmentation on a Northern archipelago.Ecology and evolution · 2016Article
- Article
- Within- and among-population impact of genetic erosion on adult fitness-related traits in the European tree frog Hyla arborea.Heredity · 2013Article
- The female perspective of mating in A. femoralis, a territorial frog with paternal care--a spatial and genetic analysis.PloS one · 2012Article
- Applications and implications of neutral versus non-neutral markers in molecular ecology.International journal of molecular sciences · 2011Review
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4 authors.
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Abstract
Populations that are small and isolated can be threatened through loss of fitness due to inbreeding. Nevertheless, an increased frequency of recessive homozygotes could increase the efficiency of selection against deleterious mutants, thus reducing inbreeding depression. In wild populations, observations of evolutionary changes determined by selection against inbreeding are few. We used microsatellite DNA markers to compare the genetic features of tadpoles immediately after hatch with those of metamorphosing froglets belonging to the same cohort in a small, isolated population of the threatened frog Rana latastei. Within a generation, the inbreeding coefficient (F IS) decreased: at hatch, F IS was significantly >0, whereas F IS was <0 after metamorphosis. Furthermore, heterozygosity increased and allelic frequencies changed over time, resulting in the loss of genotypes at metamorphosis that were present in hatchlings. One microsatellite locus exhibited atypically large F ST values, suggesting it might be linked to a locus under selection. These results support the hypothesis that strong selection against the most inbred genotypes occurred among early life-history stages in our population. Selective forces can promote changes that can affect population dynamics and should be considered in conservation planning.
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