ArticleEvolutionary applications2010
Cryptic vector divergence masks vector-specific patterns of infection: an example from the marine cycle of Lyme borreliosis.
Article in Evolutionary applications, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 74 citations in OpenAlex.
- High-throughput microfluidic real-time PCR as a promising tool in disease ecology.The Journal of animal ecology · 2025Article
- How cryptic animal vectors of fungi can influence forest health in a changing climate and how to anticipate them.Applied microbiology and biotechnology · 2025Review
- Molecular identification, genotyping and phylogenetic analysis ofFrontiers in microbiology · 2025Article
- A crucial nexus: PhylogeneticCurrent research in parasitology & vector-borne diseases · 2024Article
- How sure are you? A web-based application to confront imperfect detection of respiratory pathogens in bighorn sheep.PloS one · 2020Article
- Parasites of seabirds: A survey of effects and ecological implications.Advances in marine biology · 2019Review
- Disease-structuredEcology and evolution · 2019Article
- Complexity and biosemiotics in evolutionary ecology of zoonotic infectious agents.Evolutionary applications · 2018Article
- Identification of spider-mite species and their endosymbionts using multiplex PCR.Experimental & applied acarology · 2018Article
- The Certainty of Uncertainty: Potential Sources of Bias and Imprecision in Disease Ecology Studies.Frontiers in veterinary science · 2018Article
- Absence of haemosporidian parasite infections in the long-lived Cory's shearwater: evidence from molecular analyses and review of the literature.Parasitology research · 2018Review
- Population structure of the soft tickInternational journal for parasitology. Parasites and wildlife · 2017Article
- Article
- Dynamics of prevalence and diversity of avian malaria infections in wild Culex pipiens mosquitoes: the effects of Wolbachia, filarial nematodes and insecticide resistance.Parasites & vectors · 2014Article
- Toxoplasma gondii exposure in arctic-nesting geese: A multi-state occupancy framework and comparison of serological assays.International journal for parasitology. Parasites and wildlife · 2014Article
- Article
- Circulation of a Meaban-like virus in yellow-legged gulls and seabird ticks in the western Mediterranean basin.PloS one · 2014Article
- Using occupancy models to investigate the prevalence of ectoparasitic vectors on hosts: An example with fleas on prairie dogs.International journal for parasitology. Parasites and wildlife · 2013Article
- Isolation and characterization of ten polymorphic microsatellite loci in Ixodes arboricola, and cross-amplification in three other Ixodes species.Experimental & applied acarology · 2013Article
- Disentangling the effects of geographic and ecological isolation on genetic differentiation.Evolution; international journal of organic evolution · 2013Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vector organisms are implicated in the transmission of close to a third of all infectious diseases. In many cases, multiple vectors (species or populations) can participate in transmission but may contribute differently to disease ecology and evolution. The presence of cryptic vector populations can be particularly problematic as differences in infection can be difficult to evaluate and may lead to erroneous evolutionary and epidemiological inferences. Here, we combine site-occupancy modeling and molecular assays to evaluate patterns of infection in the marine cycle of Lyme borreliosis, involving colonial seabirds, the tick Ixodes uriae, and bacteria of the Borrelia burgdorferi s.l. complex. In this cycle, the tick vector consists of multiple, cryptic (phenotypically undistinguishable but genetically distinct) host races that are frequently found in sympatry. Our results show that bacterial detection varies strongly among tick races leading to vector-specific biases if raw counts are used to calculate Borrelia prevalence. These differences are largely explained by differences in infection intensity among tick races. After accounting for detection probabilities, we found that overall prevalence in this system is higher than previously suspected and that certain vector-host combinations likely contribute more than others to the local dynamics and large-scale dispersal of Borrelia spirochetes. These results highlight the importance of evaluating vector population structure and accounting for detection probability when trying to understand the evolutionary ecology of vector-borne diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.