ArticleEvolutionary applications2009
Towards evolution-proof malaria control with insecticides.
Article in Evolutionary applications, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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Who cites it
59 citing papers in PubMed, 91 citations in OpenAlex.
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- Sexual transmission of Anopheles gambiae densovirus (AgDNV) leads to disseminated infection in mated females.Parasites & vectors · 2022Article
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- Potential metabolic resistance mechanisms to ivermectin in Anopheles gambiae: a synergist bioassay study.Parasites & vectors · 2021Article
- Elucidating the Mechanism ofTropical medicine and infectious disease · 2020Article
- Efficacy of vector control tools against malaria-infected mosquitoes.Scientific reports · 2019Article
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- Indoor residual spray bio-efficacy and residual activity of a clothianidin-based formulation (SumiShieldMalaria journal · 2019Article
- Winning the Tug-of-War Between Effector Gene Design and Pathogen Evolution in Vector Population Replacement Strategies.Frontiers in genetics · 2019Review
- DEET Efficacy Increases With Age in the Vector Mosquitoes Anopheles gambiae s.s. and Aedes albopictus (Diptera: Culicidae).Journal of medical entomology · 2018Article
- Modelling the impact of insecticide-based control interventions on the evolution of insecticide resistance and disease transmission.Parasites & vectors · 2018Article
- Insights from agriculture for the management of insecticide resistance in disease vectors.Evolutionary applications · 2018Article
- Putting evolution in elimination: Winning our ongoing battle with evolving malaria mosquitoes and parasites.Evolutionary applications · 2018Review
- Rethinking the extrinsic incubation period of malaria parasites.Parasites & vectors · 2018Review
- Review
- Anopheles gambiae larvae mount stronger immune responses against bacterial infection than adults: evidence of adaptive decoupling in mosquitoes.Parasites & vectors · 2017Article
- The importance of temperature fluctuations in understanding mosquito population dynamics and malaria risk.Royal Society open science · 2017Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As many strategies to control malaria use insecticides against adult mosquitoes, control is undermined by the continual evolution of resistant mosquitoes. Here we suggest that using alternative insecticides, or conventional insecticides in alternative ways might enable effective control, but delay considerably or prevent the evolution of resistance. Our reasoning relies on an epidemiological and an evolutionary principle: (i) the epidemiology of malaria is strongly influenced by the life-span of mosquitoes, as most infected mosquitoes die before the malaria parasite has completed its development; and (ii) evolutionary pressure is strongest in young individuals, for selection on individuals that have completed most of their reproduction has little evolutionary effect. It follows from these principles, first, that insecticides that kill mosquitoes several days after exposure can delay considerably the evolution of resistance and, second, that the evolution of resistance against larvicides can actually benefit control, if it is associated with shorter life-span or reduced biting in adults. If a late-acting insecticide and a larvicide are combined, the evolution of resistance against larvicides can in some circumstances prevent the evolution of resistance against the more effective, late-acting insecticide, leading to sustainable, effective control. We discuss several potential options to create such insecticides, focussing on biopesticides.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.