ArticleBiomechanics and modeling in mechanobiology2015
Simulation of short-term pressure regulation during the tilt test in a coupled 3D-0D closed-loop model of the circulation.
Article in Biomechanics and modeling in mechanobiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 48 citations in OpenAlex.
- Computational Analysis of Disease Progression in Pediatric Pulmonary Arterial Hypertension.ArXiv · 2025Article
- Walking-induced inertial effects on the cardiovascular system.Frontiers in network physiology · 2025Article
- Nonlinear Closed-Loop Predictive Control of Heart Rate and Blood Pressure Using Vagus Nerve Stimulation: An In Silico Study.IEEE transactions on bio-medical engineering · 2023Article
- A Computational Study of Dynamic Obstruction in Type B Aortic Dissection.Journal of biomechanical engineering · 2023Article
- Data-driven computational models of ventricular-arterial hemodynamics in pediatric pulmonary arterial hypertension.Frontiers in physiology · 2022Article
- Data Driven Control of Vagus Nerve Stimulation for the Cardiovascular System: AnFrontiers in physiology · 2022Article
- Development of a computational fluid dynamic model to investigate the hemodynamic impact of REBOA.Frontiers in physiology · 2022Article
- Cardiovascular Response to Posture Changes: Multiscale Modeling andFrontiers in physiology · 2022Article
- CRIMSON: An open-source software framework for cardiovascular integrated modelling and simulation.PLoS computational biology · 2021Article
- Characterization of Post-Operative Hemodynamics Following the Norwood Procedure Using Population Data and Multi-Scale Modeling.Frontiers in physiology · 2021Article
- Mathematical modeling of the cardiovascular autonomic control in healthy subjects during a passive head-up tilt test.Scientific reports · 2020Article
- Multiscale Modeling Framework of Ventricular-Arterial Bi-directional Interactions in the Cardiopulmonary Circulation.Frontiers in physiology · 2020Article
- Position Paper Computational Cardiology.IEEE journal of biomedical and health informatics · 2019Article
- Patient-Specific Modeling of Hemodynamics: Supporting Surgical Planning in a Fontan Circulation Correction.Journal of cardiovascular translational research · 2018Review
- High Spatial Resolution Multi-Organ Finite Element Modeling of Ventricular-Arterial Coupling.Frontiers in physiology · 2018Article
- Patient-specific modeling of right coronary circulation vulnerability post-liver transplant in Alagille's syndrome.PloS one · 2018Article
- Article
- The Use of Biophysical Flow Models in the Surgical Management of Patients Affected by Chronic Thromboembolic Pulmonary Hypertension.Frontiers in physiology · 2018Article
- Toward translating near-infrared spectroscopy oxygen saturation data for the non-invasive prediction of spatial and temporal hemodynamics during exercise.Biomechanics and modeling in mechanobiology · 2017Article
- Reproducing Patient-Specific Hemodynamics in the Blalock-Taussig Circulation Using a Flexible Multi-Domain Simulation Framework: Applications for Optimal Shunt Design.Frontiers in pediatrics · 2017Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 2 countries.
Funding
Abstract
Short-term fluctuations in arterial pressures arising from normal physiological function are buffered by a negative feedback system known as the arterial baroreflex. Initiated by altered biomechanical stretch in the vessel wall, the baroreflex coordinates a systemic response that alters heart rate, cardiac contractility and peripheral vessel vasoconstriction. In this work, a coupled 3D-0D formulation for the short-term pressure regulation of the systemic circulation is presented. Including the baroreflex feedback mechanisms, a patient-specific model of the large arteries is subjected to a simulated head up tilt test. Comparative simulations with and without baroreflex control highlight the critical role that the baroreflex has in regulating variations in pressures within the systemic circulation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.