Evidence map›Paper›PMID 25567289›Full record

Trial reportImplementation science : IS2015

Economic evaluation of the practical approach to lung health and informal provider interventions for improving the detection of tuberculosis and chronic airways disease at primary care level in Malawi: study protocol for cost-effectiveness analysis.

Elvis Gama, Jason Madan, Hastings Banda, Bertie Squire, Rachael Thomson, Ireen Namakhoma

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Implementation science : IS, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. The 'Practical Approach to Lung Health' in sub-Saharan Africa: a systematic review.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2016
    Pooled it
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elvis GamaCentre for Applied Health Research and Delivery (CAHRD), Liverpool School of Tropical Medicine, Pembroke Place, L3 5QA, Liverpool, UK. elvis.gama@lstmed.ac.uk.
Jason MadanWarwick Medical School, University of Warwick, Coventry, UK. j.j.madan@warwick.ac.uk.
Hastings BandaReach Trust, ᅟ, Lilongwe, Malawi. hastings@reachtrust.org.
Bertie SquireCentre for Applied Health Research and Delivery (CAHRD), Liverpool School of Tropical Medicine, Pembroke Place, L3 5QA, Liverpool, UK. bertie.squire@lstmed.ac.uk.
Rachael ThomsonCentre for Applied Health Research and Delivery (CAHRD), Liverpool School of Tropical Medicine, Pembroke Place, L3 5QA, Liverpool, UK. r.thomson@lstmed.ac.uk.
Ireen NamakhomaReach Trust, ᅟ, Lilongwe, Malawi. ireen@reachtrust.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic airway diseases pose a big challenge to health systems in most developing countries, particularly in Sub-Saharan Africa. A diagnosis for people with chronic or persistent cough is usually delayed because of individual and health system barriers. However, delayed diagnosis and treatment facilitates further transmission, severity of disease with complications and mortality. The objective of this study is to assess the cost-effectiveness of the practical approach to lung health strategy, a patient-centred approach for diagnosis and treatment of common respiratory illnesses in primary healthcare settings, as a means of strengthening health systems to improve the quality of management of respiratory diseases. METHODS/

designEconomic evaluation nested in a cluster randomised controlled trial with three arms will be performed. Measures of effectiveness and costs for all arms of the study will be obtained from the cluster randomised controlled clinical trial. The main outcome measures are a combined rate of major respiratory diseases milestones and process indicators extracted from the practical approach to lung health strategy. For analysis, descriptive as well as regression techniques will be used. A cost-effectiveness analysis will be performed according to intention-to-treat principle and from a societal perspective. Cost-effectiveness ratios will be calculated using bootstrapping techniques. DISCUSSION: We hope to demonstrate the cost-effectiveness of the practical approach to lung health and informal healthcare providers, see an improvement in patients' quality of life, achieve a reduction in the duration and occurrence of episodes and the chronicity of respiratory diseases, and are able to report a decrease in the social cost. If the practical approach to lung health and informal healthcare provider's interventions are cost-effective, they could be scaled up to all primary healthcare centres.

trial registrationPACTR: PACTR201411000910192.

Indexed as

AsthmaBronchiectasisClinical ProtocolsCost-Benefit AnalysisCoughDeveloping CountriesHealth Care CostsHumansMalawiPatient CarePrimary Health CarePulmonary Disease, Chronic ObstructiveQuality ImprovementTuberculosis, Pulmonary

Identifiers

PMID25567289
PMCPMC4302070

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.