ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2015
Percutaneous balloon kyphoplasty of malignant lesions of the spine: a prospective consecutive study in 115 patients.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The role of minimally invasive surgery within a multidisciplinary approach for patients with metastatic spine disease over a decade: A systematic review.Neuro-oncology · 2024Pooled it
- Properties and clinical application safety of antibiotic-loaded bone cement in kyphoplasty.Journal of orthopaedic surgery and research · 2019Trial
- Surgical findings and precautions for removing cement that leaked into the spinal canal due to balloon kyphoplasty: illustrative cases.Journal of neurosurgery. Case lessons · 2025Article
- Surgical options for metastatic spine tumors: WFNS spine committee recommendations.Neurosurgical review · 2024Review
- Comparison of three techniques in the surgical management of metastatic vertebral fracture with posterior wall damage: a retrospective study.Journal of orthopaedic surgery and research · 2023Article
- Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review.Current oncology (Toronto, Ont.) · 2022Review
- Clinical application of a modified percutaneous vertebroplasty instrument in vertebral body biopsy in adults.BMC musculoskeletal disorders · 2022Article
- Interventional Therapies for Pain in Cancer Patients: a Narrative Review.Current pain and headache reports · 2021Review
- Balloon Kyphoplasty in the Treatment of Neoplastic Spine Lesions: A Systematic Review.Global spine journal · 2019Review
- Minimally Invasive Surgical Techniques for Management of Painful Metastatic and Primary Spinal Tumors.Cureus · 2017Review
- Evaluation of the relevance of surgery in a retrospective case series of patients who underwent the surgical treatment of a symptomatic spine metastasis from lung cancer.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2016Article
- The Michel Benoist and Robert Mulholland yearly European spine journal review: a survey of the "surgical and research" articles in the European spine journal, 2015.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2016Article
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Authors and funding
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Abstract
purposeTo evaluate the benefits of minimally invasive balloon kyphoplasty (BKP) in patients with cancer and painful pathologic vertebral lesions.
methodsIn this longitudinal, prospective, consecutive study, patients received BKP at one or more vertebral levels. The BKP procedure was guided by computed tomographic fluoroscopy. Orthopaedic bone tamps were inflated to create a cavity and the fracture was stabilised using viscous polymethylmethacrylate bone cement. After the procedure, early mobilisation was encouraged.
resultsOverall, 115 patients (52.2% with vertebral fractures) received BKP. The majority (82.6%) of patients received BKP as a stand-alone procedure. BKP treatment provided significant (P<0.0001) improvements in Visual Analogue Scale (VAS)-pain (median change: -4), Oswestry Disability Index (ODI; mean change: -53.2), and Karnofsky Performance Status (KPS; median change: 15) scores at 6 and 12 months. In total, 23% of patients achieved increased vertebral height (7.4% mean improvement in angle index). The presence of height restoration and the number of levels treated did not affect VAS or ODI scores; improvements in KPS scores were numerically higher in patients who received BKP plus additional surgery (15-20) compared with stand-alone BKP (10-15). Mean hospital times were 7.2±6.5 days. The majority (97.4%) of patients showed no complications related to the procedure; three patients (2.6%) had a temporary radiculopathy. Incidences of cement leakage were observed in 40 patients (34.8%).
conclusionsMinimally invasive BKP provided excellent long-term palliation of pain and improved mobility in patients with cancer and painful osteolytic spinal lesions or vertebral fractures.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.