ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2015
Langerhans cell histiocytosis causing acute optic neuropathy.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- Unusual sites of bone involvement in Langerhans cell histiocytosis: a systematic review of the literature.Orphanet journal of rare diseases · 2021Pooled it
- Population-Based Incidence and Outcomes of Compressive Optic Neuropathy.American journal of ophthalmology · 2022Article
- Endoscopic Resection of Pediatric Skull Base Tumors: An Evidence-Based Review.Journal of neurological surgery. Part B, Skull base · 2019Article
- A Case of Multi-System Langerhans Cell Histiocytosis with Local Invasion of the Orbital Apex.Case reports in ophthalmologyArticle
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeLangerhans cell histiocytosis (LCH) arising from the skull base is a rare acute optic neuropathy cause. We describe a clinical approach for the purpose of optic nerve decompression and simultaneous lesion excision. This is the first case of visual improvement following decompression operation via endoscopic endonasal approach for acute optic neuropathy that is produced by LCH.
methodsAn 11-year-old boy presented with a 2-week history of visual deterioration. Radiological evidence of compressive optic neuropathy by an expansile soft tissue mass around the optic canal was observed. The patient underwent an endoscopic endonasal optic nerve decompression and subtotal tumor removal.
resultsHis visual impairment improved dramatically after the operation.
conclusionsAcute optic neuropathy can be elicited by LCH arising in the sphenoid-ethmoid bone. Early decompression is the key to vision salvage. An endoscopic endonasal approach may be a good therapeutic option in this situation.
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