ReviewFrontiers in bioengineering and biotechnology2014
Production of Fatty Acid-derived valuable chemicals in synthetic microbes.
Review in Frontiers in bioengineering and biotechnology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 67 citations in OpenAlex.
- Dissecting Holistic Metabolic Acclimatization ofBiology · 2024Article
- Tuning Fatty Acid Profile and Yield inBioengineering (Basel, Switzerland) · 2023Article
- Article
- Current advances in alteration of fatty acid profile in Rhodotorula toruloides: a mini-review.World journal of microbiology & biotechnology · 2023Review
- Biofuels and Nanocatalysts: Python Boosting Visualization of Similarities.Materials (Basel, Switzerland) · 2023Article
- EngineeringSynthetic and systems biotechnology · 2022Review
- Insights into cyanobacterial alkane biosynthesis.Journal of industrial microbiology & biotechnology · 2022Review
- Valorisation of algal biomass to value-added metabolites: emerging trends and opportunities.Phytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2022Review
- Effects of pH and Osmotic Changes on the Metabolic Expressions ofMetabolites · 2022Article
- Mass spectrometry based metabolomics approach on the elucidation of volatile metabolites formation in fermented foods: A mini review.Food science and biotechnology · 2021Review
- A Brief Journey into the History of and Future Sources and Uses of Fatty Acids.Frontiers in nutrition · 2021Review
- Microbial lipases and their industrial applications: a comprehensive review.Microbial cell factories · 2020Review
- Bacterial Biotransformation of Oleic Acid: New Findings on the Formation of γ-Dodecalactone and 10-Ketostearic Acid in the Culture ofMolecules (Basel, Switzerland) · 2020Article
- Sustainable production of FAEE biodiesel using the oleaginous yeast Yarrowia lipolytica.MicrobiologyOpen · 2020Article
- Photosynthetic Conversion of Carbon Dioxide to Oleochemicals by Cyanobacteria: Recent Advances and Future Perspectives.Frontiers in microbiology · 2020Review
- A comprehensive genome-scale model forMetabolic engineering communications · 2019Article
- Distinctive Formation of Volatile Compounds in Fermented Rice Inoculated by Different Molds, Yeasts, and Lactic Acid Bacteria.Molecules (Basel, Switzerland) · 2019Article
- Chimeric Fatty Acyl-Acyl Carrier Protein Thioesterases Provide Mechanistic Insight into Enzyme Specificity and Expression.Applied and environmental microbiology · 2018Article
- An engineered fatty acid synthase combined with a carboxylic acid reductase enables de novo production of 1-octanol inBiotechnology for biofuels · 2018Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fatty acid derivatives, such as hydroxy fatty acids, fatty alcohols, fatty acid methyl/ethyl esters, and fatty alka(e)nes, have a wide range of industrial applications including plastics, lubricants, and fuels. Currently, these chemicals are obtained mainly through chemical synthesis, which is complex and costly, and their availability from natural biological sources is extremely limited. Metabolic engineering of microorganisms has provided a platform for effective production of these valuable biochemicals. Notably, synthetic biology-based metabolic engineering strategies have been extensively applied to refactor microorganisms for improved biochemical production. Here, we reviewed: (i) the current status of metabolic engineering of microbes that produce fatty acid-derived valuable chemicals, and (ii) the recent progress of synthetic biology approaches that assist metabolic engineering, such as mRNA secondary structure engineering, sensor-regulator system, regulatable expression system, ultrasensitive input/output control system, and computer science-based design of complex gene circuits. Furthermore, key challenges and strategies were discussed. Finally, we concluded that synthetic biology provides useful metabolic engineering strategies for economically viable production of fatty acid-derived valuable chemicals in engineered microbes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.