Association Between Microbial Bioburden and Healing Outcomes in Venous Leg Ulcers: A Review of the Evidence.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

24 citing papers in PubMed, 57 citations in OpenAlex.

1. Wound Healing Property of a Novel Thermo-Reversible Wound Gel With Lasting Antimicrobial and Antibiofilm Activity.International wound journal · 2026
   Article
2. The Association of Systemic Inflammation, Wound Bioburden and Total Bacterial Counts With Healing Outcomes in Older Adults With Chronic Venous Leg Ulcers.International wound journal · 2025
   Article
3. Microbiota shifts in fracture-related infections and pathogenic transitions identified by 16S rDNA sequencing.Scientific reports · 2025
   Article
4. Temporal dynamics and interrelations of cytokines, neutrophil proteins, exudation, and bacterial colonization in epidermal wound healing.Frontiers in medicine · 2025
   Article
5. Associations Among Wound-Related Factors Including Biofilm, Wound-Related Symptoms and Systemic Inflammation in Older Adults with Chronic Venous Leg Ulcers.Advances in wound care · 2024
   Observational
6. Evaluation of stem-cell therapies in companion animal disease models: a concise review (2015-2023).Stem cells (Dayton, Ohio) · 2024
   Review
7. Wound Microbiota and Its Impact on Wound Healing.International journal of molecular sciences · 2023
   Review
8. Homocysteine and Inflammatory Cytokines in the Clinical Assessment of Infection in Venous Leg Ulcers.Antibiotics (Basel, Switzerland) · 2022
   Article
9. Recurrent Cellulitis: Who is at Risk and How Effective is Antibiotic Prophylaxis?International journal of general medicine · 2022
   Review
10. Microbiological Status of Venous Leg Ulcers and Its Predictors: A Single-Center Cross-Sectional Study.International journal of environmental research and public health · 2021
    Article
11. Comparison Between Cultivation and Sequencing Based Approaches for Microbiota Analysis in Swabs and Biopsies of Chronic Wounds.Frontiers in medicine · 2021
    Article
12. Biofilm-Innate Immune Interface: Contribution to Chronic Wound Formation.Frontiers in immunology · 2021
    Review
13. Development of a Model to Predict Healing of Chronic Wounds Within 12 Weeks.Advances in wound care · 2020
    Article
14. Metabolic modelling of chronic wound microbiota predicts mutualistic interactions that drive community composition.Journal of applied microbiology · 2019
    Article
15. The detrimental impact of extracellular bacterial proteases on wound healing.International wound journal · 2017
    Review
16. Activated Mesenchymal Stem Cells Interact with Antibiotics and Host Innate Immune Responses to Control Chronic Bacterial Infections.Scientific reports · 2017
    Article
17. More Pathogenicity or Just More Pathogens?-On the Interpretation Problem of Multiple Pathogen Detections with Diagnostic Multiplex Assays.Frontiers in microbiology · 2017
    Review
18. Fighting Off Wound Pathogens in Horses with Honeybee Lactic Acid Bacteria.Current microbiology · 2016
    Article
19. The phagocytic fitness of leucopatches may impact the healing of chronic wounds.Clinical and experimental immunology · 2016
    Article
20. Infection in Venous Leg Ulcers: Considerations for Optimal Management in the Elderly.Drugs & aging · 2016
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

1 author at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.