ArticleBMC psychology2013
Neuropsychological profile according to the clinical stage of young persons presenting for mental health care.
Article in BMC psychology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The progress in the field of clinical staging for mental disorders within the last decade: an updated systematic review.Frontiers in psychiatry · 2024Pooled it
- Transdiagnostic Clinical Staging in Youth Mental Health: A primer for clinical practice.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2025Review
- Transdiagnostic Clinical Staging for Childhood Mental Health: An Adjunctive Tool for Classifying Internalizing and Externalizing Syndromes that Emerge in Children Aged 5-11 Years.Clinical child and family psychology review · 2022Article
- Article
- Subjective cognitive functioning in relation to changes in levels of depression and anxiety in youth over 3 months of treatment.BJPsych open · 2020Article
- Clinical Stage Transitions in Persons Aged 12 to 25 Years Presenting to Early Intervention Mental Health Services With Anxiety, Mood, and Psychotic Disorders.JAMA psychiatry · 2019Article
- Article
- Evaluating differential developmental trajectories to adolescent-onset mood and psychotic disorders.BMC psychiatry · 2013Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundClinical staging of mental disorders proposes that individuals can be assessed at various sub-syndromal and later developed phases of illness. As an adjunctive rating, it may complement traditional diagnostic silo-based approaches. In this study, we sought to determine the relationships between clinical stage and neuropsychological profile in young persons presenting to youth-focused mental health services.
methodsNeuropsychological testing of 194 help-seeking young people (mean age 22.6 years, 52% female) and 50 healthy controls. Clinical staging rated 94 persons as having an 'attenuated syndrome' (stage 1b) and 100 with a discrete or persistent disorder (stage 2/3).
resultsThe discrete disorder group (stage 2/3) showed the most impaired neuropsychological profile, with the earlier stage (1b) group showing an intermediate profile, compared to controls. Greatest impairments were seen in verbal memory and executive functioning. To address potential confounds created by 'diagnosis', profiles for those with a mood syndrome or disorder but not psychosis were also examined and the neuropsychological impairments for the stage 2/3 group remained.
conclusionsThe degree of neuropsychological impairment in young persons with mental disorders appears to discriminate those with attenuated syndromes from those with a discrete disorder, independent of diagnostic status and current symptoms. Our findings suggest that neuropsychological assessment is a critical aspect of clinical evaluation of young patients at the early stages of a major psychiatric illness.
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