ArticleThe European physical journal. Special topics2014
Hydrodynamics of DNA confined in nanoslits and nanochannels.
Article in The European physical journal. Special topics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Single-molecule capture, release, and dynamical manipulation via reversible electrokinetic confinement (RECON).Science advances · 2025Article
- Block copolymer-assembled nanopore arrays enable ultrasensitive label-free DNA detection.Nanoscale horizons · 2025Article
- Knot Formation on DNA Pushed Inside Chiral Nanochannels.Polymers · 2023Article
- Steering particles via micro-actuation of chemical gradients using model predictive control.Biomicrofluidics · 2023Article
- Knot formation of dsDNA pushed inside a nanochannel.Scientific reports · 2022Article
- Electrostatic/entropic macromolecule manipulation in nanochannel. Swapping of macromolecule locations.Journal of molecular modeling · 2019Article
- Nanoplumbing with 2D Metamaterials.Small (Weinheim an der Bergstrasse, Germany) · 2019Article
- Evaluation of Blob Theory for the Diffusion of DNA in Nanochannels.Macromolecules · 2018Article
- The Statistical Segment Length of DNA: Opportunities for Biomechanical Modeling in Polymer Physics and Next-Generation Genomics.Journal of biomechanical engineering · 2018Article
- Kirkwood diffusivity of long semiflexible chains in nanochannel confinement.Macromolecules · 2015Article
- Evaluation of the Kirkwood approximation for the diffusivity of channel-confined DNA chains in the de Gennes regime.Biomicrofluidics · 2015Article
- Brownian motion in confined geometries.The European physical journal. Special topics · 2014Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Modeling the dynamics of a confined, semi exible polymer is a challenging problem, owing to the complicated interplay between the configurations of the chain, which are strongly affected by the length scale for the confinement relative to the persistence length of the chain, and the polymer-wall hydrodynamic interactions. At the same time, understanding these dynamics are crucial to the advancement of emerging genomic technologies that use confinement to stretch out DNA and "read" a genomic signature. In this mini-review, we begin by considering what is known experimentally and theoretically about the friction of a wormlike chain such as DNA confined in a slit or a channel. We then discuss how to estimate the friction coefficient of such a chain, either with dynamic simulations or via Monte Carlo sampling and the Kirk-wood pre-averaging approximation. We then review our recent work on computing the diffusivity of DNA in nanoslits and nanochannels, and conclude with some promising avenues for future work and caveats about our approach.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.