Evidence map›Paper›PMID 25566180›Full record

ArticleFrontiers in neurology2014

Predictive factors of neurological complications and one-month mortality after liver transplantation.

Katherine A Fu, Joseph DiNorcia, Linda Sher, Shamsha A Velani, Shahrzad Akhtar, Laura A Kalayjian, Nerses Sanossian

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Clinical Impact and Risk Factors of Seizure After Liver Transplantation: A Nested Case-Control Study.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Katherine A FuKeck School of Medicine, University of Southern California , Los Angeles, CA , USA.
Joseph DiNorciaKeck School of Medicine, University of Southern California , Los Angeles, CA , USA ; Department of Hepatobiliary, Pancreas and Abdominal Organ Transplant Surgery, University of Southern California , Los Angeles, CA , USA.
Linda SherKeck School of Medicine, University of Southern California , Los Angeles, CA , USA ; Department of Hepatobiliary, Pancreas and Abdominal Organ Transplant Surgery, University of Southern California , Los Angeles, CA , USA.
Shamsha A VelaniKeck School of Medicine, University of Southern California , Los Angeles, CA , USA ; Department of Neurology, University of Southern California , Los Angeles, CA , USA.
Shahrzad AkhtarKeck School of Medicine, University of Southern California , Los Angeles, CA , USA.
Laura A KalayjianKeck School of Medicine, University of Southern California , Los Angeles, CA , USA ; Department of Neurology, University of Southern California , Los Angeles, CA , USA.
Nerses SanossianKeck School of Medicine, University of Southern California , Los Angeles, CA , USA ; Department of Neurology, University of Southern California , Los Angeles, CA , USA.
University of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeurological complications are common after orthotopic liver transplantation (OLT). We aimed to characterize the risk factors associated with neurological complications and mortality among patients who underwent OLT in the post-model for end-stage liver disease (MELD) era.

methodsIn a retrospective review, we evaluated 227 consecutive patients at the Keck Hospital of the University of Southern California before and after OLT to define the type and frequency of and risk factors for neurological complications and mortality.

resultsNeurological complications were common (n = 98), with encephalopathy being most frequent (56.8%), followed by tremor (26.5%), hallucinations (11.2%), and seizure (8.2%). Factors associated with neurological complications after OLT included preoperative dialysis, hepatorenal syndrome, renal insufficiency, intra-operative dialysis, preoperative encephalopathy, preoperative mechanical ventilation, and infection. Preoperative infection was an independent predictor of neurological complications (OR 2.83, 1.47-5.44). One-month mortality was 8.8% and was independently associated with urgent re-transplant, preoperative intubation, and intra-operative arrhythmia.

conclusionNeurological complications are common in patients undergoing OLT in the post-MELD era, with encephalopathy being most frequent. An improved understanding of the risk factors related to both neurological complications and one-month mortality post-transplantation can better guide perioperative care and help improve outcomes among OLT patients.

Indexed as

liver transplantmortalityneurological complications

Identifiers

PMID25566180
PMCPMC4269112
OpenAlexW2080186691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.