Evidence map›Paper›PMID 25565882›Full record

ArticleInternational journal of general medicine2015

Treatment of localized neuropathic pain of different etiologies with the 5% lidocaine medicated plaster - a case series.

Rudolf Likar, Susanne Demschar, Ingo Kager, Stefan Neuwersch, Wolfgang Pipam, Reinhard Sittl

Open access · goldAbstract read
In one paragraph

Article in International journal of general medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Treatment Strategies for Generator Pocket Pain.Pain medicine (Malden, Mass.) · 2021
    Article
  4. Early experience with topical meloxicam and lidocaine combination for the treatment of vulvodynia.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2018
    Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Rudolf LikarDepartment of Anesthesiology and Intensive Care, Hospital Klagenfurt, Klagenfurt, Austria.
Susanne DemscharDepartment of Anesthesiology and Intensive Care, Hospital Klagenfurt, Klagenfurt, Austria.
Ingo KagerDepartment of Anesthesiology and Intensive Care, Hospital Klagenfurt, Klagenfurt, Austria.
Stefan NeuwerschDepartment of Anesthesiology and Intensive Care, Hospital Klagenfurt, Klagenfurt, Austria.
Wolfgang PipamDepartment of Anesthesiology and Intensive Care, Hospital Klagenfurt, Klagenfurt, Austria.
Reinhard SittlDepartment of Anesthesiology, Interdisciplinary Pain Centre, University Hospital Erlangen, Erlangen, Germany.
Klinikum Klagenfurt · ATUniversitätsklinikum Erlangen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the efficacy and safety of the topical 5% lidocaine medicated plaster in the treatment of localized neuropathic pain. STUDY

designThis was a case series at an Austrian pain clinic, using retrospective analysis. PATIENTS AND

methodsData of 27 patients treated for localized neuropathic pain with the 5% lidocaine medicated plaster were retrospectively analyzed. Assessment included changes in overall pain intensity, in intensity of different pain qualities, and of hyperalgesia and allodynia, and changes in sleep quality.

resultsPatients (17 female, ten male; mean age 53.4±11.4 years) presented mainly with dorsalgia (16 patients) or postoperative/posttraumatic pain (seven patients); one patient suffered from both. The mean overall pain intensity prior to treatment with lidocaine medicated plaster was 8.4±1.2 on the 11-point Likert scale. In the majority of cases, the lidocaine plaster was applied concomitantly with preexisting pain medication (81.5% of the patients). During the 6-month observation period, overall mean pain intensity was reduced by almost 5 points (4.98) to 3.5±2.6. Substantial reductions were also observed for neuralgiform pain (5 points from 7.9±2.6 at baseline) and burning pain (3 points from 5.2±4.1). Sleep quality improved from 4.6±2.6 at baseline to 5.5±1.8. Stratification by pain diagnosis showed marked improvements in overall pain intensity for patients with dorsalgia or postoperative/posttraumatic pain. The lidocaine plaster was well tolerated.

conclusionOverall, topical treatment with the 5% lidocaine medicated plaster was associated with effective pain relief and was well tolerated.

Indexed as

5% lidocaine medicated plasterdorsalgialocalized neuropathic painpostoperative/posttraumatic paintopical analgesic

Identifiers

PMID25565882
PMCPMC4278790
OpenAlexW2060845860

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.