ArticleDrug design, development and therapy2015
Microemulsion of babassu oil as a natural product to improve human immune system function.
Article in Drug design, development and therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 43 citations in OpenAlex.
- Dietary Starch-Extract Complexes from Cerrado Fruits Modulate Oxidative Stress in Mononuclear Cells from Normoglycemic and Diabetic Individuals.Antioxidants (Basel, Switzerland) · 2025Article
- Preparation and In Vitro Characterization of Alkyl Polyglucoside-Based Microemulsion for Topical Administration of Curcumin.Pharmaceutics · 2023Article
- Copaiba Oil Resin Exerts an Additive Effect to Babassu Oil on Behavioral Changes in Human Endometriotic Cell Cultures.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Effects of Modified Melatonin Release on Human Colostrum Neutrophils to Induce Death in the MCF-7 Cell Line.International journal of cell biology · 2022Article
- In Vitro and In Vivo Wound Healing and Anti-Inflammatory Activities of Babassu Oil (Evidence-based complementary and alternative medicine : eCAM · 2020Article
- Anti-Inflammatory Activity of Babassu Oil and Development of a Microemulsion System for Topical Delivery.Evidence-based complementary and alternative medicine : eCAM · 2017Article
- Formation of microemulsions for using as cosmeceutical delivery systems: effects of various components and characteristics of some formulations.Drug delivery and translational research · 2016Article
- Nanoparticles of barium induce apoptosis in human phagocytes.International journal of nanomedicine · 2015Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to develop and characterize a babassu oil microemulsion system and determine the effect of this microemulsion on the functional activity of phagocytes.
methodsThe microemulsion was formulated using distilled water, babassu as the oil phase component, Sorbitan monooleate-Span 80(®) (SP), Polysorbate 80-Tween 80(®) (TW), and 1-butanol (BT). Pseudoternary diagrams were prepared, and microemulsion diagram regions were preselected. Rheological characterization and preliminary and accelerated stability tests were performed. The effect of the microemulsion on the interactions between leukocytes and bacteria was determined by superoxide release, phagocytosis, and microbicidal activity.
resultsThe developed formulation SP/TW/BT (4.2/4.8/1.0) was classified as oil/water, showed a Newtonian profile, and had linear viscosity. When we assessed the interaction of the microemulsion or babassu oil with phagocytes, we observed an increase in superoxide, phagocytosis, and microbicidal activity.
conclusionThe babassu oil microemulsion system is an option for future applications, including for vaccine delivery systems. Babassu oil is a natural product, so is an alternative for future immunotherapy strategies, in particular for infectious diseases.
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