Evidence map›Paper›PMID 25565580›Full record

ArticleNature communications2015

Volume and porosity thermal regulation in lipid mesophases by coupling mobile ligands to soft membranes.

Lucia Parolini, Bortolo M Mognetti, Jurij Kotar, Erika Eiser, Pietro Cicuta, Lorenzo Di Michele

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 111 citations in OpenAlex.

  1. Article
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  4. Haptotactic Motion of Multivalent Vesicles Along Ligand-Density Gradients.Langmuir : the ACS journal of surfaces and colloids · 2025
    Article
  5. Bottom-up synthetic immunology.Nature nanotechnology · 2024
    Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. DNA as grabbers and steerers of quantum emitters.Nanophotonics (Berlin, Germany) · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Amphiphilic DNA nanostructures for bottom-up synthetic biology.Chemical communications (Cambridge, England) · 2021
    Review
  18. DNA self-organization controls valence in programmable colloid design.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Lucia ParoliniBiological and Soft Systems Sector, Cavendish Laboratory, University of Cambridge, Cambridge CB3 0HE, UK.
Bortolo M MognettiInterdisciplinary Center for Nonlinear Phenomena and Complex Systems &Service de Physique des Systémes Complexes et Mécanique Statistique, Université libre de Bruxelles, Campus Plaine, CP 231, Boulevard du Triomphe, Brussels B-1050, Belgium.
Jurij KotarBiological and Soft Systems Sector, Cavendish Laboratory, University of Cambridge, Cambridge CB3 0HE, UK.
Erika EiserOptoelectronics Group, Cavendish Laboratory, University of Cambridge, Cambridge CB3 0HE, UK.
Pietro CicutaBiological and Soft Systems Sector, Cavendish Laboratory, University of Cambridge, Cambridge CB3 0HE, UK.
Lorenzo Di MicheleBiological and Soft Systems Sector, Cavendish Laboratory, University of Cambridge, Cambridge CB3 0HE, UK.
University of Cambridge · GBUniversité Libre de Bruxelles · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Short DNA linkers are increasingly being exploited for driving-specific self-assembly of Brownian objects. DNA-functionalized colloids can assemble into ordered or amorphous materials with tailored morphology. Recently, the same approach has been applied to compliant units, including emulsion droplets and lipid vesicles. The liquid structure of these substrates introduces new degrees of freedom: the tethers can diffuse and rearrange, radically changing the physics of the interactions. Unlike droplets, vesicles are extremely deformable and DNA-mediated adhesion causes significant shape adjustments. We investigate experimentally the thermal response of pairs and networks of DNA-tethered liposomes and observe two intriguing and possibly useful collective properties: negative thermal expansion and tuneable porosity of the liposome networks. A model providing a thorough understanding of this unexpected phenomenon is developed, explaining the emergent properties out of the interplay between the temperature-dependent deformability of the vesicles and the DNA-mediated adhesive forces.

Indexed as

LigandsModels, TheoreticalBase SequenceColloidsDNAImage Processing, Computer-AssistedLiposomesMembranesMicroscopy, FluorescenceMolecular Sequence DataNanoparticlesPorosityTemperatureColloidsDNALigandsLiposomes

Identifiers

PMID25565580
PMCPMC4354032
OpenAlexW2009063977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.