ArticleJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2015
The Association Between BMI and QCT-Derived Proximal Hip Structure and Strength in Older Men: A Cross-Sectional Study.
Article in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Pooled it
- Complete Blood Count Parameters and Bone Health: Clinical and Experimental Evidence (Endocrinol Metab 2025;40:811-20, Jeonghoon Ha et al.).Endocrinology and metabolism (Seoul, Korea) · 2026Article
- Complete Blood Count Parameters and Bone Health: Clinical and Experimental Evidence (Endocrinol Metab 2025;40:811-20, Jeonghoon Ha et al.).Endocrinology and metabolism (Seoul, Korea) · 2026Article
- Association between body mass index and lumbar spine volumetric bone mineral density in diabetic and non-diabetic patients.World journal of diabetes · 2025Article
- The association between relative fat mass (RFM) and lumbar bone density in US adults: Insight from 2011-2018 NHANES.PloS one · 2025Article
- Parametrized statistical appearance and shape modelling strategy to predict proximal and diaphyseal femoral fractures.Frontiers in bioengineering and biotechnology · 2025Article
- Biomechanical perspectives on image-based hip fracture risk assessment: advances and challenges.Frontiers in endocrinology · 2025Review
- Exploring the impact of body mass index on the accuracy of vertebral bone quality in determining bone mineral density in patients undergoing lumbar fusion surgery.Journal of orthopaedic surgery and research · 2024Article
- The association between body mass index and bone mineral density in older adults: a cross-sectional study of community population in Beijing.BMC musculoskeletal disorders · 2024Article
- Article
- Obesity and Bone Health: A Complex Relationship.International journal of molecular sciences · 2022Review
- Development and Internal Validation of Supervised Machine Learning Algorithm for Predicting the Risk of Recollapse Following Minimally Invasive Kyphoplasty in Osteoporotic Vertebral Compression Fractures.Frontiers in public health · 2022Article
- The Saturation Effect of Obesity on Bone Mineral Density for Older People: The NHANES 2017-2020.Frontiers in endocrinology · 2022Article
- Association Between Hemoglobin Levels and Osteoporosis in Chinese Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
- Differential impact of osteoporosis, sarcopenia and obesity on physical performance in aging men.Endocrine connections · 2021Article
- The Relation Between Calcaneus Stiffness Index as a Measure of Bone Density and Body Mass Index in an Egyptian Cohort.Journal of multidisciplinary healthcare · 2019Article
- The obesity paradox and osteoporosis.Eating and weight disorders : EWD · 2018Review
- Low bone toughness in the TallyHO model of juvenile type 2 diabetes does not worsen with age.Bone · 2018Article
- Hypogonadal Men with Higher Body Mass Index have Higher Bone Density and Better Bone Quality but Reduced Muscle Density.Calcified tissue international · 2017Article
- Obesity, Type 2 Diabetes and Bone in Adults.Calcified tissue international · 2017Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Although higher body mass index (BMI) is associated with higher bone mineral density, recent evidence indicates that increased BMI may not be consistently associated with reduced hip fracture risk. Moreover, substantial proportions of hip fractures occur among overweight and obese men and women. The role of increased BMI and obesity on bone density, structure, and strength at the hip is not well understood. We conducted cross-sectional analyses between BMI and various density and structure measures derived from quantitative computed tomography (QCT)-scans of the proximal femur, in 3067 men (mean age: 73 y) from the Osteoporotic Fractures in Men Study (MrOS). Finite element (FE) analysis of hip QCT scans was performed for a subcohort of 672 men to provide a measure of femoral strength for a simulated sideways fall. The impact force was estimated using patient-specific weight and height information. Multivariable general linear models were used to examine the associations between BMI and hip QCT measures. The relationship of BMI with hip QCT measures was significantly different between men categorized as non-obese and obese (P for interaction ≤ 0.014). For non-obese men (BMI < 30), increasing BMI was associated with higher integral, cortical and trabecular vBMD, integral volume, cross-sectional area, and percent cortical volume (all p < 0.001). For obese men (BMI ≥30), increasing BMI was not associated with any of those parameters. In addition, compared to non-obese men, obese men had a higher hip strength, but also a higher ratio of impact force to strength (P < 0.0001), in theory increasing their risk of hip fracture despite their increased strength. These results provide a better understanding of hip fracture risk in obese men.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.