Evidence map›Paper›PMID 25565483›Full record

ArticlePreventive medicine2015

Prevalence of colonoscopy before age 50.

Carolyn M Rutter, Robert T Greenlee, Eric Johnson, Azadeh Stark, Sheila Weinmann, Aruna Kamineni, Kenneth Adams, Chyke A Doubeni

Open access · greenAbstract read
In one paragraph

Article in Preventive medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trends in and factors associated with family physician-performed screening colonoscopies in the United States: 2016-2021.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Carolyn M RutterRAND Corporation, Santa Monica, CA, United States. Electronic address: crutter@rand.org.
Robert T GreenleeMarshfield Clinic Research Foundation, Epidemiology Research Center, Marshfield, WI, United States.
Eric JohnsonGroup Health Research Institute, Seattle,` WA, United States.
Azadeh StarkGeisinger Center for Health Research, Danville, PA, United States; Henry Ford Health System, Department of Pathology, Detroit, MI, United States.
Sheila WeinmannKaiser Permanente, Center for Health Research Northwest, Portland, OR, United States.
Aruna KamineniGroup Health Research Institute, Seattle,` WA, United States.
Kenneth AdamsMinnesota Department of Health, Minnesota Cancer Surveillance System, Saint Paul, MN, United States.
Chyke A DoubeniDepartment of Family Medicine and Community Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Kaiser Permanente Washington Health Research Institute · USHenry Ford Health System · USKaiser Permanente Center for Health Research · USMarshfield Clinic · USMinnesota Department of Health · USRAND Corporation · USUniversity of Pennsylvania · US

Funding

The HMO Cancer Research Network (CRN)U19CA079689 · NCI · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI WAGNER, EDWARD H · 1999 to 2011
$62.6M
Studying Colorectal Cancer Effectiveness of Screening Strategies (SuCCESS)U54CA163261 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI CHUBAK, JESSICA · 2011 to 2017
$7.3M
Effectiveness of Screening Colonoscopy in Reducing Deaths from Colorectal CancerU01CA151736 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI DOUBENI, CHYKE ABADAMA · 2011 to 2015
$4.5M
SEARCH: Cancer Screening Effectiveness and Research in Community-based HealthcareRC2CA148576 · NCI · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI BUIST, DIANA SM, DOUBENI, CHYKE ABADAMA · 2009 to 2009
$2.0M
SEARCH: Cancer Screening Effectiveness and Research in Community-based HealthcareUC2CA148576 · NCI · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI BUIST, DIANA SM, DOUBENI, CHYKE ABADAMA · 2010 to 2010
$2.0M
NCI NIH HHS 5U54CA163261NCI NIH HHS RC2 CA148576NCI NIH HHS U01 CA151736NCI NIH HHS U19 CA079689NCI NIH HHS U19 CA79689NCI NIH HHS U54 CA163261NCI NIH HHS UC2 CA148576NCI NIH HHS UC2CA148576
6 · The paper itself

Abstract

objectiveDescribe the prevalence of colonoscopy before age 50, when guidelines recommend initiation of colorectal cancer screening for average risk individuals.

methodWe assembled administrative health records that captured receipt of colonoscopy between 40 and 49-years of age for a cohort of 204,758 50-year-old members of four US health plans and used backward recurrence time models to estimate trends in receipt of colonoscopy before age 50 and variation in early colonoscopy by age and sex. We also used self-reported receipt of colonoscopy from 27,157 40- to 49-year-old respondents to the 2010 National Health Interview Survey (NHIS) to estimate the association between early colonoscopy and sex, race/ethnicity, and geographic location based on logistic regression models that accounted for the complex NHIS sampling design.

resultsAbout 5% of the health plan cohort had a record of colonoscopy before age 50. Receipt of early colonoscopy increased significantly from 1999 to 2010 (test for linear trend, p<0.0001), was more likely among women than men (RR=1.9, 95% CI 1.14-1.24) and in the east coast health plan compared to west coast and Hawaii plans. The NHIS analysis found that early colonoscopy was more likely in Northeastern residents compared to residents in the West (odds ratio=1.75, 95% CI 1.28-2.39).

conclusionColonoscopy before age 50 is increasingly common.

Indexed as

AdultAge FactorsCohort StudiesColonic NeoplasmsColonoscopyEarly Detection of CancerFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsSex FactorsUnited StatesColorectal cancer screeningHMO Cancer Research NetworkScreening uptake

Identifiers

PMID25565483
PMCPMC4482462
OpenAlexW1976418979

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.