Evidence map›Paper›PMID 25565030›Full record

ArticleNature structural & molecular biology2015

Technologies to probe functions and mechanisms of long noncoding RNAs.

Ci Chu, Robert C Spitale, Howard Y Chang

Abstract read
PubMed Publisher
In one paragraph

Article in Nature structural & molecular biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed.

  1. Protein-Centric Mapping of RNA-DNA Interactions with RedChIP.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  2. Review
  3. Review
  4. Review
  5. Roles of LncRNAs in the Pathogenesis of Pulmonary Hypertension.Reviews in cardiovascular medicine · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Endothelial cells LEENE on noncoding RNAs in diabetic vasculopathy.The Journal of clinical investigation · 2023
    Article
  10. Review
  11. Article
  12. Review
  13. LncRNAs in domesticated animals: from dog to livestock species.Mammalian genome : official journal of the International Mammalian Genome Society · 2022
    Review
  14. Advances in multi-omics study of biomarkers of glycolipid metabolism disorder.Computational and structural biotechnology journal · 2022
    Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Non-coding RNAs in chromatin folding and nuclear organization.Cellular and molecular life sciences : CMLS · 2021
    Review

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ci ChuProgram in Epithelial Biology, Stanford University School of Medicine, Stanford, California, USA.
Robert C Spitale1] Program in Epithelial Biology, Stanford University School of Medicine, Stanford, California, USA. [2] Department of Pharmaceutical Sciences, University of California at Irvine, Irvine, California, USA.
Howard Y Chang1] Program in Epithelial Biology, Stanford University School of Medicine, Stanford, California, USA. [2] Howard Hughes Medical Institute, Stanford University, Stanford, California, USA.

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

Thousands of long noncoding RNAs (lncRNAs) have been discovered, but their functional characterization has been slowed by a limited set of research tools. Here we review emerging RNA-centric methods to interrogate the intrinsic structure of lncRNAs as well as their genomic localization and biochemical partners. Understanding these technologies, including their advantages and caveats, and developing them in the future will be essential to progress from description to comprehension of the myriad roles of lncRNAs.

Indexed as

Molecular BiologyRNA, Long NoncodingRNA, Long Noncoding

Identifiers

PMID25565030

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.