ArticleAmerican journal of infection control2015
A decade of investment in infection prevention: a cost-effectiveness analysis.
Article in American journal of infection control, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Health Economic Evaluations in Intensive Care: An Updated Systematic Review.Critical care explorations · 2025Pooled it
- Rethinking Tuberculosis Morbidity Quantification: A Systematic Review and Critical Appraisal of TB Disability Weights in Cost-Effectiveness Analyses.PharmacoEconomics · 2024Pooled it
- Safe Healthcare Facilities: A Systematic Review on the Costs of Establishing and Maintaining Environmental Health in Facilities in Low- and Middle-Income Countries.International journal of environmental research and public health · 2021Pooled it
- Pooled it
- Economic Evaluation of Quality Improvement Interventions for Bloodstream Infections Related to Central Catheters: A Systematic Review.JAMA internal medicine · 2016Pooled it
- Costs of Infection Prevention Practices in Long-Term Care Settings: A Systematic Review.Nursing economic$Pooled it
- Cost-effectiveness of an Environmental Cleaning Bundle for Reducing Healthcare-associated Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020Trial
- Economic Evaluation of a Catheter-Associated Urinary Tract Infection Prevention Program in Nursing Homes.Journal of the American Geriatrics Society · 2018Trial
- Quantifying Quality Care: The Financial Argument for Protecting Time for Quality Improvement Work by Infectious Diseases Physicians.Open forum infectious diseases · 2026Article
- [Balancing act between infection protection by hygiene measures and sustainability in surgery].Chirurgie (Heidelberg, Germany) · 2026Review
- Risk Factor Assessment and Predictive Modeling for Ventilator-Associated Pneumonia: Design and Clinical Implementation of an Artificial Intelligence-Enhanced Early Detection Framework Using Multisource Data Analytics.The clinical respiratory journal · 2025Article
- Global surgery is stronger when infection prevention and control is incorporated: a commentary and review of the surgical infection landscape.BMC surgery · 2024Review
- Cost-effectiveness analysis of CTZ/TAZ for the treatment of ventilated hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia in Japan.BMC health services research · 2024Article
- Implementation of a novel color additive for bleach disinfectant wipes enhances cleaning performance in an academic medical center.Infection control and hospital epidemiology · 2023Article
- A comprehensive comparison of biofilm formation and capsule production for bacterial survival on hospital surfaces.Biofilm · 2023Article
- Socioeconomic burden of pneumonia due to multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa in Korea.Scientific reports · 2022Article
- Economic burden attributable to healthcare-associated infections in tertiary public hospitals of Central China: a multi-centre case-control study.Epidemiology and infection · 2022Article
- An Overview of Healthcare Associated Infections and Their Detection Methods Caused by Pathogen Bacteria in Romania and Europe.Journal of clinical medicine · 2022Review
- Article
- Factors Facilitating and Hindering the Use of Newly Acquired Positioning Skills in Clinical Practice: A Longitudinal Survey.Frontiers in medicine · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundHealth care-associated infection (HAI) rates have fallen with the development of multifaceted infection prevention programs. These programs require ongoing investments, however. Our objective was to examine the cost-effectiveness of hospitals' ongoing investments in HAI prevention in intensive care units (ICUs).
methodsFive years of Medicare data were combined with HAI rates and cost and quality of life estimates drawn from the literature. Life-years (LYs), quality-adjusted LYs (QALYs), and health care expenditures with and without central line-associated bloodstream infection (CLABSI) and/or ventilator-associated pneumonia (VAP), as well as incremental cost-effectiveness ratios (ICERs) of multifaceted HAI prevention programs, were modeled.
resultsTotal LYs and QALYs gained per ICU due to infection prevention programs were 15.55 LY and 9.61 QALY for CLABSI and 10.84 LY and 6.55 QALY for VAP. Reductions in index admission ICU costs were $174,713.09 for CLABSI and $163,090.54 for VAP. The ICERs were $14,250.74 per LY gained and $23,277.86 per QALY gained.
conclusionsMultifaceted HAI prevention programs are cost-effective. Our results underscore the importance of maintaining ongoing investments in HAI prevention. The welfare benefits implied by the advantageous ICERs would be lost if the investments were suspended.
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