Observational studyAnnals of surgery2016
Relative Contributions of Complications and Failure to Rescue on Mortality in Older Patients Undergoing Pancreatectomy.
Observational study in Annals of surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 78 citations in OpenAlex.
- External Validation of the International Study Group for Pancreatic Surgery Complexity Grading System for Minimally Invasive Pancreatoduodenectomy: Insights From the IGOMIPS Registry.Annals of surgery · 2026Article
- Review
- Textbook outcome following pancreaticoduodenectomy in elderly patients: age-stratified analysis and predictive factors.Updates in surgery · 2025Article
- Robotic Versus Open Pancreatoduodenectomy With Vein Resection and Reconstruction: A Propensity Score-Matched Analysis.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024Article
- Perioperative predictive factors of failure to rescue following highly advanced hepatobiliary-pancreatic surgery: a single-institution retrospective study.World journal of surgical oncology · 2023Article
- Article
- Timing of Postoperative Stroke and Risk of Mortality After Noncardiac Surgery: A Cohort Study.Journal of clinical medicine research · 2023Article
- Observational
- Trends in Textbook Outcomes over Time: Are Optimal Outcomes Following Complex Gastrointestinal Surgery for Cancer Increasing?Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Article
- Machine learning predicts unpredicted deaths with high accuracy following hepatopancreatic surgery.Hepatobiliary surgery and nutrition · 2021Article
- In-hospital Mortality Following Pancreatoduodenectomy: a Comprehensive Analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020Article
- Failure to rescue in surgical patients: A review for acute care surgeons.The journal of trauma and acute care surgery · 2019Review
- Leakage of an Invagination Pancreaticojejunostomy May Have an Influence on Mortality.Journal of pancreatic cancer · 2018Article
- Indication for en bloc pancreatectomy with colectomy: when is it safe?Surgical endoscopy · 2018Article
- Systematic review and meta-analysis of frailty as a predictor of morbidity and mortality after major abdominal surgery.BJS open · 2017Review
- Complications and failure to rescue following laparoscopic or open gastrectomy for gastric cancer: a propensity-matched analysis.Surgical endoscopy · 2017Article
- Surgical rescue: The next pillar of acute care surgery.The journal of trauma and acute care surgery · 2017Article
- Laparoscopic pancreaticoduodenectomy in A-92-older Chinese patient for cancer of head of the pancreas: A Case report.Medicine · 2017Article
- Relative impact of surgeon and hospital volume on operative mortality and complications following pancreatic resection in Medicare patients.The Journal of surgical research · 2016Article
- Comparison of observed to predicted outcomes using the ACS NSQIP risk calculator in patients undergoing pancreaticoduodenectomy.Journal of surgical oncology · 2016Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundFor pancreatectomy patients, mortality increases with increasing age. Our study evaluated the relative contribution of overall postoperative complications and failure to rescue rates on the observed increased mortality in older patients undergoing pancreatic resection at specialized centers.
methodsWe identified 2694 patients who underwent pancreatic resection from the American College of Surgeons' National Surgical Quality Improvement Pancreatectomy Demonstration Project at 37 high-volume centers. Overall morbidity and in-hospital mortality were determined in patients younger than 80 years (N = 2496) and 80 years or older (N = 198). Failure to rescue was the number of deaths in patients with complications divided by the total number of patients with postoperative complications.
resultsNo significant differences were observed between patients younger than 80 years and those 80 years or older in the rates of overall complications (41.4% vs 39.4%, P = 0.58). In-hospital mortality increased in patients 80 years or older compared to patients younger than 80 years (3.0% vs 1.1%, P = 0.02). Failures to rescue rates were higher in patients 80 years or older (7.7% vs 2.7%, P = 0.01). Across 37 high-volume centers, unadjusted complication rates ranged from 25.0% to 72.2% and failure to rescue rates ranged from 0.0% to 25.0%. Among patients with postoperative complications, comorbidities associated with failure to rescue were ascites, chronic obstructive pulmonary disease, and diabetes. Complications associated with failure to rescue included acute renal failure, septic shock, and postoperative pulmonary complications.
conclusionsIn experienced hands, the rates of complications after pancreatectomy in patients 80 years or older compared to patients younger than 80 years were similar. However, when complications occurred, older patients were more likely to die. Interventions to identify and aggressively treat complications are necessary to decrease mortality in vulnerable older patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.