Evidence map›Paper›PMID 25563703›Full record

ArticleJournal of oncology practice2015

Correlation of clinical stage and performance status with quality of life in patients seen in a pancreas multidisciplinary clinic.

Shalini Moningi, Amanda J Walker, Charles C Hsu, Jennifer Barsky Reese, Jing-Ya Wang, Katherine Y Fan, Lauren M Rosati, Daniel A Laheru, Matthew J Weiss, Christopher L Wolfgang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of oncology practice, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Machine learning-based random forest for predicting decreased quality of life in thyroid cancer patients after thyroidectomy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Trial
  4. Trial
  5. Review
  6. Article
  7. Article
  8. Quality of Life in Patients with Pancreatic Cancer-A Literature Review.International journal of environmental research and public health · 2023
    Review
  9. Review
  10. The fear of cancer recurrence and progression in patients with pancreatic cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  11. Article
  12. Article
  13. Observational
  14. Beyond Performance Status.Clinical oncology (Royal College of Radiologists (Great Britain)) · 2020
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shalini MoningiJohns Hopkins University School of Medicine, Baltimore, MD; and University of California, San Francisco, San Francisco, CA.
Amanda J WalkerJohns Hopkins University School of Medicine, Baltimore, MD; and University of California, San Francisco, San Francisco, CA.
Charles C HsuJohns Hopkins University School of Medicine, Baltimore, MD; and University of California, San Francisco, San Francisco, CA.
Jennifer Barsky ReeseJohns Hopkins University School of Medicine, Baltimore, MD; and University of California, San Francisco, San Francisco, CA.
Jing-Ya WangJohns Hopkins University School of Medicine, Baltimore, MD; and University of California, San Francisco, San Francisco, CA.
Katherine Y FanJohns Hopkins University School of Medicine, Baltimore, MD; and University of California, San Francisco, San Francisco, CA.
Lauren M RosatiJohns Hopkins University School of Medicine, Baltimore, MD; and University of California, San Francisco, San Francisco, CA.
Daniel A LaheruJohns Hopkins University School of Medicine, Baltimore, MD; and University of California, San Francisco, San Francisco, CA.
Matthew J WeissJohns Hopkins University School of Medicine, Baltimore, MD; and University of California, San Francisco, San Francisco, CA.
Christopher L WolfgangJohns Hopkins University School of Medicine, Baltimore, MD; and University of California, San Francisco, San Francisco, CA.
Timothy M PawlikJohns Hopkins University School of Medicine, Baltimore, MD; and University of California, San Francisco, San Francisco, CA.
Joseph M HermanJohns Hopkins University School of Medicine, Baltimore, MD; and University of California, San Francisco, San Francisco, CA jherma15@jhmi.edu.

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI Rosalie Wollett · 1985 to 2026
$208.6M
NCI NIH HHS P30 CA006973
6 · The paper itself

Abstract

introductionThe objectives of this study were to evaluate quality of life (QoL) in patients presenting to the Johns Hopkins Pancreas Multidisciplinary Clinic (PMDC), and to examine associations between disease status, performance status, and QoL in order to identify patient subgroups that are most at risk for reduced QoL. PATIENTS AND

methodsData from 77 patients were evaluated. At initial presentation, disease and performance status were assessed, as well as QoL, which was obtained with the European Organisation for Research and Treatment of Cancer QLQ-PAN26 questionnaire. Statistical analyses examined associations between QoL, disease status, and performance status.

resultsDigestive symptoms (P < .003) significantly differed by pancreatic disease status (resectable, resected, locally advanced, and metastatic). Patients with a worse performance status, defined as Eastern Cooperative Oncology Group ≥ 1, were more likely to report symptomatic pancreatic pain (P = .001), digestive symptoms (P = .017), cachexia (P = .004), and ascites (P < .001) compared with patients with a performance status of 0. The majority (92%) of patients reported a significant fear of future health problems, regardless of disease status or performance status.

conclusionAlthough several measures of QoL have been observed in all patients, certain measures appear to correlate specifically with worse disease status. Therefore, routine assessment of QoL is suggested in order to guide treatment decisions. Further investigation on optimizing the use of QoL measures and patient-reported outcomes to better tailor management is warranted.

Indexed as

Quality of LifeSeverity of Illness IndexAgedCancer Care FacilitiesCohort StudiesCross-Sectional StudiesFemaleHumansMaleMiddle AgedNeoplasm StagingPancreatic NeoplasmsSelf Report

Identifiers

PMID25563703
PMCPMC4811042

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.