Evidence map›Paper›PMID 25563538›Full record

ArticleJournal of occupational and environmental medicine2015

Isocyanates and human health: multistakeholder information needs and research priorities.

James E Lockey, Carrie A Redlich, Robert Streicher, Andrea Pfahles-Hutchens, Pertti Bert J Hakkinen, Gary L Ellison, Philip Harber, Mark Utell, John Holland, Andrew Comai and 1 more

Erratum issuedAbstract read
In one paragraph

Article in Journal of occupational and environmental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Microcapsules of Poly(butylene adipate-ACS applied polymer materials · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Occupational Exposure to Diisocyanates in the European Union.Annals of work exposures and health · 2021
    Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

11 authors.

James E LockeyFrom the Department of Environmental Health (Dr Lockey), Division of Occupational and Environmental Medicine, Pulmonary Division--Department of Internal Medicine, University of Cincinnati College of Medicine, Ohio; Yale Occupational and Environmental Medicine (Dr Redlich), Yale School of Medicine, New Haven, Conn; Division of Applied Research and Technology (Dr Streicher), National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, Ohio; Risk Assessment Division (Ms Pfahles-Hutchens), Office of Chemical Safety and Pollution Prevention, US Environmental Protection Agency, Washington, DC; Office of Clinical Toxicology (Dr Hakkinen), Specialized Information Services, National Library of Medicine, National Institutes of Health; Epidemiology and Genomics Research Program (Dr Ellison), Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Md; Mel and Enid Zuckerman College of Public Health (Dr Harber), University of Arizona, Tucson; Occupational and Environmental Medicine (Dr Utell), University of Rochester Medical Center, NY; Holland Associates (Dr Holland), Palo Alto, Calif; International Union (Mr Comai), UAW, Health and Safety, Detroit, Mich; and Department of Family Practice (Dr White), University of British Columbia, and Canadian Institute for the Relief of Pain and Disability, Vancouver, Canada.
Carrie A Redlich
Robert Streicher
Andrea Pfahles-Hutchens
Pertti Bert J Hakkinen
Gary L Ellison
Philip Harber
Mark Utell
John Holland
Andrew Comai
Marc White

Funding

WORKER HEALTH &SAFETY TRAINING COOPERATIVE AGREEMENTU45ES006180 · NIEHS · INTERNATIONAL UNION, UAW OF AMER AFL-CIO · PI SIVIN, DARIUS D · 1992 to 2024
$23.3M
Canadian Institutes of Health ResearchNIEHS NIH HHS U45 ES006180
6 · The paper itself

Abstract

objectivesTo outline the knowledge gaps and research priorities identified by a broad base of stakeholders involved in the planning and participation of an international conference and research agenda workshop on isocyanates and human health held in Potomac, Maryland, in April 2013.

methodsA multimodal iterative approach was used for data collection including preconference surveys, review of a 2001 consensus conference on isocyanates, oral and poster presentations, focused break-out sessions, panel discussions, and postconference research agenda workshop.

resultsParticipants included representatives of consumer and worker health, health professionals, regulatory agencies, academic and industry scientists, labor, and trade associations.

conclusionsRecommendations were summarized regarding knowledge gaps and research priorities in the following areas: worker and consumer exposures; toxicology, animal models, and biomarkers; human cancer risk; environmental exposure and monitoring; and respiratory epidemiology and disease, and occupational health surveillance.

Indexed as

Biomedical ResearchOccupational ExposureBiomarkersCongresses as TopicConsensusConsumer Product SafetyEnvironmental ExposureEnvironmental MonitoringHealth PrioritiesHumansIsocyanatesModels, AnimalNeoplasmsOccupational DiseasesOccupational HealthRespiratory Tract DiseasesBiomarkersIsocyanates

Identifiers

PMID25563538
PMCPMC4286799

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.