ArticleJournal of the American Chemical Society2015
Negative dielectrophoretic capture and repulsion of single cells at a bipolar electrode: the impact of faradaic ion enrichment and depletion.
Article in Journal of the American Chemical Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Recent advances in electrochemiluminescence sensing for in vitro cell analysis: a review.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025Review
- Thermal bubble single-cell printing chip: High-throughput, wide-field, and efficient.Biomicrofluidics · 2024Article
- Microfluidic-Based Electrical Operation and Measurement Methods in Single-Cell Analysis.Sensors (Basel, Switzerland) · 2024Review
- On-chip dielectrophoretic single-cell manipulation.Microsystems & nanoengineering · 2024Review
- Quantification of capture efficiency, purity, and single-cell isolation in the recovery of circulating melanoma cells from peripheral blood by dielectrophoresis.Lab on a chip · 2023Article
- Massive and efficient encapsulation of single cells in monodisperse droplets and collagen-alginate microgels using a microfluidic device.Frontiers in bioengineering and biotechnology · 2023Article
- Article
- Enhancement of Binding Kinetics on Affinity Substrates Using Asymmetric Electroosmotic Flow on a Sinusoidal Bipolar Electrode.Micromachines · 2022Article
- Bipolar Electrochemical Measurement of Enantiomeric Excess with Inherently Chiral Polymer Actuators.ACS measurement science au · 2021Article
- Filtering and continuously separating microplastics from water using electric field gradients formed electrochemically in the absence of buffer.Chemical science · 2021Article
- Focusing, sorting, and separating microplastics by serial faradaic ion concentration polarization.Chemical science · 2020Article
- Defining Cell Cluster Size by Dielectrophoretic Capture at an Array of Wireless Electrodes of Several Distinct Lengths.Micromachines · 2019Article
- Integration of marker-free selection of single cells at a wireless electrode array with parallel fluidic isolation and electrical lysis.Chemical science · 2019Article
- Electric and Electrochemical Microfluidic Devices for Cell Analysis.Frontiers in chemistry · 2019Review
- A Self-Digitization Dielectrophoretic (SD-DEP) Chip for High-Efficiency Single-Cell Capture, On-Demand Compartmentalization, and Downstream Nucleic Acid Analysis.Angewandte Chemie (International ed. in English) · 2018Article
- Nanoslit design for ion conductivity gradient enhanced dielectrophoresis for ultrafast biomarker enrichment in physiological media.Biomicrofluidics · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
This paper describes the dielectrophoretic (DEP) forces generated by a bipolar electrode (BPE) in a microfluidic device and elucidates the impact of faradaic ion enrichment and depletion (FIE and FID) on electric field gradients. DEP technologies for manipulating biological cells provide several distinct advantages over other cell-handling techniques including label-free selectivity, inexpensive device components, and amenability to single-cell and array-based applications. However, extension to the array format is nontrivial, and DEP forces are notoriously short-range, limiting device dimensions and throughput. BPEs present an attractive option for DEP because of the ease with which they can be arrayed. Here, we present experimental results demonstrating both negative DEP (nDEP) attraction and repulsion of B-cells from each a BPE cathode and anode. The direction of nDEP force in each case was determined by whether the conditions for FIE or FID were chosen in the experimental design. We conclude that FIE and FID zones generated by BPEs can be exploited to shape and extend the electric field gradients that are responsible for DEP force.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.