Evidence map›Paper›PMID 25561989›Full record

ArticleWideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques2014

Dynamics of type 2 diabetes mellitus laboratory remission after Roux-en-Y gastric bypass in patients with body mass index lower than 35 kg/m(2) and higher than 35 kg/m(2) in a 3-year observation period.

Łukasz Kaska, Monika Proczko, Jarek Kobiela, Tomasz Jerzy Stefaniak, Zbigniew Śledzinski

Abstract read
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Article in Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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4 citing papers in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Łukasz KaskaDepartment of General, Endocrine and Transplant Surgery, Medical University of Gdansk, Gdansk, Poland.
Monika ProczkoDepartment of General, Endocrine and Transplant Surgery, Medical University of Gdansk, Gdansk, Poland.
Jarek KobielaDepartment of General, Endocrine and Transplant Surgery, Medical University of Gdansk, Gdansk, Poland.
Tomasz Jerzy StefaniakDepartment of General, Endocrine and Transplant Surgery, Medical University of Gdansk, Gdansk, Poland.
Zbigniew ŚledzinskiDepartment of General, Endocrine and Transplant Surgery, Medical University of Gdansk, Gdansk, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBariatric surgery as treatment of type 2 diabetes mellitus (T2DM) in morbidly obese patients is becoming common. Although a large number of studies demonstrating high efficacy of bariatric methods in diabetics with body mass index (BMI) < 35 kg/m(2) have been published, this promising solution is still not accepted enough even in the era of a diabetes offensive.

aimTo analyze the dynamics of T2DM remission in patients with BMI < 35 kg/m(2) and > 35 kg/m(2) after Roux-en-Y gastric bypass (RYGB). MATERIAL AND

methodsData of 30 patients with BMI < 35 kg/m(2) and 82 with BMI > 35 kg/m(2) who underwent RYGB between 2007 and 2010 were collected from a prospectively designed database. The laboratory resolution of T2DM was determined by fasting plasma glucose (FPG ≤ 100 mg/dl) and glycosylated hemoglobin (HbA1c ≤ 6%).

resultsThe T2DM regression was observed in 80% of the patients with BMI < 35 kg/m(2) and 83% in a group with BMI > 35 kg/m(2) 1 year after RYGB and about 80% 2 and 3 years after the operation in both groups. Normalization of average HbA1c and FPG was observed in the BMI > 35 kg/m(2) group after 3 months, while in the BMI < 35 kg/m(2) group it was reached 6 months postoperatively. Changes in main markers of T2DM were parallel with the BMI decrease 3-12 months after RYGB, but early resolution in some patients was observed independently of weight loss.

conclusionsThe mid-term observation of patients after RYGB revealed the laboratory remission of T2DM. Ultimate evaluation of T2DM markers 3 years after surgery demonstrates high effectiveness of RYGB in managing T2DM in both groups.

Indexed as

body mass index below 35 kg/m2remissionRoux-en-Y gastric bypasssurgical treatmenttype 2 diabetes mellitus

Identifiers

PMID25561989
PMCPMC4280414

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