Evidence map›Paper›PMID 25561930›Full record

ArticleIranian journal of pharmaceutical research : IJPR2015

Phytochemical Investigation on Euphorbia macrostegia (Persian wood spurge).

Somayeh Zare, Mehrorang Ghaedi, Ramin Miri, Sven Heiling, Mojtaba Asadollahi, Ian T Baldwin, Amir Reza Jassbi

Abstract read
In one paragraph

Article in Iranian journal of pharmaceutical research : IJPR, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Phytochemical Characterization ofFood science & nutrition · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Phytochemical Analysis and Biological Activity ofIranian journal of pharmaceutical research : IJPR · 2022
    Article
  6. In vitro anti-proliferative activities of the sterols and fatty acids isolated from the Persian Gulf sponge; Axinella sinoxea.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2019
    Article
  7. The effect ofBioscience reports · 2019
    Article
  8. Trace Element Analysis by ICP-MS and Chemometric Approach in SomeIranian journal of pharmaceutical research : IJPR · 2019
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Somayeh ZareMedicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. ; Department of Phytochemistry, Yasouj University, Yasouj 75914-353, Iran.
Mehrorang GhaediDepartment of Phytochemistry, Yasouj University, Yasouj 75914-353, Iran.
Ramin MiriMedicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Sven HeilingDepartment of Molecular Ecology, Max Planck Institute for Chemical Ecology, Hans -Knöll -Strasse 8, D-07745 Jena, Germany.
Mojtaba AsadollahiMedicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Ian T BaldwinDepartment of Molecular Ecology, Max Planck Institute for Chemical Ecology, Hans -Knöll -Strasse 8, D-07745 Jena, Germany.
Amir Reza JassbiMedicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Euphorbia macrostegia or Persian wood spurge is one of the seventeen endemic plants of this genus in Iran. Three triterpenoids, 24-methylenecycloartan-3β-ol (1), butyrospermol (2) and cycloartenol (3) and three diglycerides, 1,2-di-O-α-linolenoyl-sn-glycerol (4), 1-O-linoleoyl-3-O-palmitoyl-sn-glycerol (5) and 1-O-α-linolenoyl-2-O-palmitoyl-sn-glycerol (6) were isolated from the hexane soluble part of methanol-dichloromethane extracts of the aerial parts of Euphorbia macrostegia Boiss. The structures of all compounds were elucidated using different spectroscopy methods including, (1)H NMR, (13)C NMR, HSQC, HMBC, EI-MS and IR. The triterpenes and the unsaturated fatty acids moieties of the diglycerides isolated from the plant were reported previously to have analgesic, anticancer, bactericidal and antifungal activity. Here, we show that E. macrostegia is a new source for the above mentioned biologically active compounds.

Indexed as

Cycloartane triterpenoidsDiglycerides of fatty acidsEuphorbiaceaeEuphorbia macrostegia

Identifiers

PMID25561930
PMCPMC4277637

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.