Evidence map›Paper›PMID 25560824›Full record

ArticleThe journal of nutrition, health & aging2015

Community-dwelling female fallers have lower muscle density in their lower legs than non-fallers: evidence from the Saskatoon Canadian Multicentre Osteoporosis Study (CaMos) cohort.

A W Frank, J P Farthing, P D Chilibeck, C M Arnold, W P Olszynski, S A Kontulainen

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in The journal of nutrition, health & aging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
8.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Review
  3. Observational
  4. Associations of Quadriceps Torque Properties with Muscle Size, Attenuation, and Intramuscular Adipose Tissue in Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2018
    Article
  5. Article
  6. Lower leg muscle density is independently associated with fall status in community-dwelling older adults.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
    Observational
  7. Article
  8. Article
  9. Article
  10. Hip Fractures Risk in Older Men and Women Associated With DXA-Derived Measures of Thigh Subcutaneous Fat Thickness, Cross-Sectional Muscle Area, and Muscle Density.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2015
    Article
  11. Lower-extremity muscle atrophy and fat infiltration after chronic spinal cord injury.Journal of musculoskeletal & neuronal interactions · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

A W FrankA.W. Frank, M.Sc., College of Kinesiology, University of Saskatchewan, 87 Campus Drive, Saskatoon, SK. S7N5B2, Canada, Phone: +1 (306) 966-1123, Fax: +1 (306) 966-6464, E-mail: andrew.frank@usask.ca.
J P Farthing
P D Chilibeck
C M Arnold
W P Olszynski
S A Kontulainen
University of Saskatchewan · CA

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

objectivesOur objectives were to determine whether peripheral quantitative computed tomography (pQCT)-derived lower leg muscle density and area, and basic functional mobility differ between community-dwelling older women who do and do not report recent falls.

designMatched case-control comparison.

settingAcademic biomedical imaging laboratory.

participants147 Women, 60 years or older (mean age 74.3 y, SD 7.7) recruited from a longitudinal, population-based cohort representing community-dwelling residents in the area of Saskatoon, Canada. MEASUREMENTS: A cross-sectional pQCT scan of the non-dominant lower leg was acquired to determine muscle density and area. Basic functional mobility (Timed Up and Go Test [TUG]) and SF36 health status were also measured. Fallers (one or more falls) and non-fallers (no falls) were grouped according to a 12-month retrospective survey and matched on measured covariates.

resultsThe muscle density of fallers (n = 35) was a median of 2.1 mg/cm3 lower (P = 0.019, 95% C.I. -3.9 to -0.1) than non-fallers (n = 78) after matching and adjusting for age, body mass index, and SF36 general health scores. Muscle area and TUG did not differ between fallers and non-fallers.

conclusionsMuscle density may serve as a physiological marker in the assessment of lower leg muscular health and fall risk in community-dwelling elderly women. These results are limited to our study population who were mostly Caucasian. Prospective studies are required for verification.

Indexed as

Accidental FallsAgedAged, 80 and overCase-Control StudiesFemaleHumansLegLongitudinal StudiesMiddle AgedMuscle, SkeletalOsteoporosis, PostmenopausalPostural BalanceResidence CharacteristicsRetrospective StudiesSaskatchewan

Identifiers

PMID25560824
PMCPMC12280507
OpenAlexW2022473590

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.