Evidence map›Paper›PMID 25560330›Full record

Trial reportGlobal journal of health science2014

The effect of 8 weeks aerobic exercise on insulin resistance in type 2 diabetes: a randomized clinical trial.

Narges Motahari-Tabari, Marjan Ahmad Shirvani, Mahbobeh Shirzad-E-Ahoodashty, Elham Yousefi-Abdolmaleki, Mojgan Teimourzadeh

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Global journal of health science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07258316 (Comparative Effects of High-Intensity Interval Training in Pre and Postmenopausal Women With Type II Diabetes Mellitus), which is not on this map. Cited by 43 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 7 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07258316 nacompletednot on this mapstarted 2025, after this paper: background citation

Comparative Effects of High-Intensity Interval Training in Pre and Postmenopausal Women With Type II Diabetes Mellitus

TypeinterventionalSponsorRiphah International UniversityRan2025 to 2026Enrolled60ConditionsDiabetes Mellitus, Type 2, Postmenopausal SymptomsArmsHigh Intensity Interval Training (warm up, Mat exercises,cycling,HIIT exercises,cool down), Control (warm up, Mat exercises,cycling,Resistance exercises,cool down)
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 7 syntheses or guidelines pooled it, 132 citations in OpenAlex.

  1. Pooled it
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  8. Trial
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  11. Review
  12. Article
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  16. Article
  17. Physical activity in metabolic syndrome.Frontiers in physiology · 2024
    Review
  18. Review
  19. Article
  20. Insulin resistance and cardiovascular disease.The Journal of international medical research · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Narges Motahari-Tabari
Marjan Ahmad ShirvaniSchool of Nursing and Midwifery,Mazandaran University of Medical Sciences, Sari, Iran. shirvani44@yahoo.com.
Mahbobeh Shirzad-E-Ahoodashty
Elham Yousefi-Abdolmaleki
Mojgan Teimourzadeh
Mazandaran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes complications are the main reasons behind morbidity and mortality preventable by healthy diet and physical activity. There are few studies about the effect of aerobic exercises on insulin resistance in human. Also various training protocols are associated with different results. Since approaches to decrease insulin resistance may be followed by more effectiveness treatment, this study assessed the effect of aerobic exercise on insulin resistance in type 2 diabetes mellitus. In this randomized clinical trial, 53 type 2 diabetic women were randomly divided into two groups as exercise (n=27) and control (n=26).The exercise protocol included warm-up by stretching and flexibility exercises for 10 m, followed by walking for 30 m with maximum intensity 60% increase in heart rate and then stretching in the seated position for 10 m, 3 times a week for 8 weeks. Resistance to insulin was assessed using Homeostasis Model Assessment of Insulin Resistance (HOMA-IR). Significant differences have been observed in insulin resistance, fasting glucose and plasma insulin between the groups after 8 weeks. There were significant differences in waist and hip circumference, BMI, plasma insulin and insulin resistance within the groups over time. In addition, the changes in waist and hip circumference, FBS, plasma insulin and insulin resistance had significant interaction with the time between the groups. The current exercise protocol has been effective in lowering plasma glucose (p = 0.05), insulin levels (p = 0.000) and insulin resistance (p = 0.02). It seems that aerobic exercises training promote the effectiveness of medical treatment in type 2 diabetes mellitus.

Indexed as

ExerciseInsulin ResistanceAnthropometryBlood GlucoseDiabetes Mellitus, Type 2FemaleHumansInsulinIranMiddle AgedTreatment OutcomeBlood GlucoseInsulin

Identifiers

PMID25560330
PMCPMC4796439
OpenAlexW2148598572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.