Macrophage-produced IL-10 limits the chemotherapy efficacy in breast cancer.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

1. Current Insights into the Role of Peripheral Blood Immune Cell Phenotypes in Resistance to Cancer Therapies.Oncology research · 2026
   Review
2. Phase Ib/II Study of Lacnotuzumab in Combination with Spartalizumab in Patients with Advanced Malignancies.Journal of immunotherapy and precision oncology · 2024
   Article
3. Crosstalk of Inflammatory Cytokines within the Breast Tumor Microenvironment.International journal of molecular sciences · 2023
   Review
4. Iranian journal of basic medical sciences · 2022
   Article
5. A Survey on the Role of Interleukin-10 in Breast Cancer: A Narrative.Reports of biochemistry & molecular biology · 2018
   Article
6. Exploring immuno-regulatory mechanisms in the tumor microenvironment: Model and design of protocols for cancer remission.PloS one · 2018
   Article
7. Correlation analysis of gene polymorphisms and β-lactam allergy.Journal of Zhejiang University. Science. B · 2015
   Article
8. Interleukin-10: A double-edged sword in breast cancer.Tzu chi medical journal
   Review
9. Comparison of the characteristics of macrophages derived from murine spleen, peritoneal cavity, and bone marrow.Journal of Zhejiang University. Science. B
   Article
10. Successful treatment of accessory breast cancer with endocrine therapyJournal of Zhejiang University. Science. B
    Article

Corrections and comments

• Comment on
  Macrophage IL-10 blocks CD8+ T cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells.2014

Authors and funding

1 author at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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