Evidence map›Paper›PMID 25559871›Full record

ArticleCognitive neuropsychiatry2015

Delusions and prediction error: clarifying the roles of behavioural and brain responses.

Philip Robert Corlett, Paul Charles Fletcher

Abstract read
In one paragraph

Article in Cognitive neuropsychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. MRI Study of the Brain Structural Characteristic in Persecutory Delusions.Bulletin of experimental biology and medicine · 2025
    Article
  6. Article
  7. Irrelevant Threats Linger and Affect Behavior in High Anxiety.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  8. Article
  9. The prediction-error hypothesis of schizophrenia: new data point to circuit-specific changes in dopamine activity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Predictive Processing, Source Monitoring, and Psychosis.Annual review of clinical psychology · 2017
    Review
  18. Article
  19. Article
  20. Prediction error, ketamine and psychosis: An updated model.Journal of psychopharmacology (Oxford, England) · 2016
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Philip Robert Corletta Department of Psychiatry, Ribicoff Research Facility , Yale University , 34 Park Street, New Haven , CT , USA.
Paul Charles Fletcher

Funding

Yale University Clinical and Translational Science Award ProgramUL1TR000142 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$31.8M
Medical Research Council G0001354NCATS NIH HHS UL1 TR000142NCATS NIH HHS UL1TR000142Wellcome Trust 095692
6 · The paper itself

Abstract

Griffiths and colleagues provided a clear and thoughtful review of the prediction error model of delusion formation [Cognitive Neuropsychiatry, 2014 April 4 (Epub ahead of print)]. As well as reviewing the central ideas and concluding that the existing evidence base is broadly supportive of the model, they provide a detailed critique of some of the experiments that we have performed to study it. Though they conclude that the shortcomings that they identify in these experiments do not fundamentally challenge the prediction error model, we nevertheless respond to these criticisms. We begin by providing a more detailed outline of the model itself as there are certain important aspects of it that were not covered in their review. We then respond to their specific criticisms of the empirical evidence. We defend the neuroimaging contrasts that we used to explore this model of psychosis arguing that, while any single contrast entails some ambiguity, our assumptions have been justified by our extensive background work before and since.

Indexed as

BrainCognitionDelusionsFunctional NeuroimagingHumansMagnetic Resonance ImagingModels, NeurologicalModels, PsychologicalPsychotic DisordersThinkingcognitive neurosciencedelusionsfunctional neuroimagingprediction error

Identifiers

PMID25559871
PMCPMC4305467

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.