Evidence map›Paper›PMID 25559847›Full record

ReviewPflugers Archiv : European journal of physiology2015

The taste of table salt.

Stephen D Roper

Open access · greenAbstract readReview
In one paragraph

Review in Pflugers Archiv : European journal of physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 77 citations in OpenAlex.

  1. Review
  2. Article
  3. Epithelial NaComprehensive Physiology · 2024
    Review
  4. Article
  5. Observational
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Taste transduction and channel synapses in taste buds.Pflugers Archiv : European journal of physiology · 2021
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Stephen D RoperDepartment of Physiology and Biophysics, Miller School of Medicine, University of Miami, Miami, FL, 33146, USA, sroper@med.miami.edu.
University of Miami · US

Funding

CHEMOSENSORY TRANSDUCTION IN TASTE CELLSR01DC000374 · NIDCD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ROPER, STEPHEN D. · 1989 to 2012
$4.2M
A new method to measure taste bud functionR01DC007630 · NIDCD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ROPER, STEPHEN D. · 2006 to 2016
$3.1M
NIDCD NIH HHS R01 DC000374NIDCD NIH HHS R01 DC007630
6 · The paper itself

Abstract

Solutions of table salt (NaCl) elicit several tastes, including of course saltiness but also sweet, sour, and bitter. This brief review touches on some of the mileposts concerning what is known about taste transduction for the Na(+) ion, the main contributor to saltiness. Electrophysiological recordings, initially from single gustatory nerve fibers, and later, integrated impulse activity from gustatory nerves led researchers to predict that Na(+) ions interacted with a surface molecule. Subsequent studies have resolved that this molecule is likely to be an epithelial sodium channel, ENaC. Other Na(+) transduction mechanisms are also present in taste buds but have not yet been identified. The specific type(s) of taste cells responsible for salt taste also remains unknown.

Indexed as

TasteTaste PerceptionAnimalsEpithelial Sodium ChannelsHumansSodiumSodium Chloride, DietaryTaste BudsEpithelial Sodium ChannelsSodiumSodium Chloride, Dietary

Identifiers

PMID25559847
PMCPMC4326615
OpenAlexW1976419496

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.