ArticleEndocrinology and metabolism (Seoul, Korea)2015
Physiological Parameters in the Blood of a Murine Stress-Induced Depression Model before and after Repeated Passive Exercise.
Article in Endocrinology and metabolism (Seoul, Korea), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Article
- Blood and affective markers of stress in Elite Airmen during a preparatory training course: A pilot study.Neurobiology of stress · 2021Article
- Aggravated mucosal and immune damage in a mouse model of ulcerative colitis with stress.Experimental and therapeutic medicine · 2019Article
- G9a-Mediated Regulation of OXT and AVP Expression in the Basolateral Amygdala Mediates Stress-Induced Lasting Behavioral Depression and Its Reversal by Exercise.Molecular neurobiology · 2016Article
- Can Exercise Make You Smarter, Happier, and Have More Neurons? A Hormetic Perspective.Frontiers in neuroscience · 2016Article
- Exercise and Depression.Endocrinology and metabolism (Seoul, Korea) · 2015Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnimal models are necessary to study the mechanism underlying the effects of exercise on depression but an effective procedure for exercise treatment and exercise effects on physiological parameters in a specific depression model need to be characterized.
methodsPhysiological parameters including lactate, partial pressue of O₂ (pO₂) and CO₂ (pCO₂) saturated O₂ (sO₂), pH, HCO₃, total CO₂ (TCO₂), and base excess extracellular fluid (BEecf) levels in the blood were measured after treatment with passive exercise in normal mice and a stress-induced depression model.
resultsNormal mice or mice that were subjected to daily 2-hour restraint for 14 days (2 hours × 14 days of restraint) were placed on a running wheel that was rotating at a speed of 9 m/min for 1 hour per day for 1 to 21 days. After repeated exercise in mice that were previously subjected to 2 hours × 14 days restraint, plasma lactate levels decreased, the levels of pO₂, sO₂, and pH tended to increase, and the levels of pCO₂ decreased in the absence of significant changes in HCO₃, TCO₂, and BEecf. However, none of these changes were additive to the stress effects or were much more severe than those induced after repeated passive exercise in normal mice.
conclusionThese results suggest that passive exercise for 1 hour daily for 14 to 21 consecutive days on a running wheel rotating at a speed of 9 m/min may be used as an exercise protocol without inducing severe additive effects on physiological burdens.
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