ArticleJournal of acquired immune deficiency syndromes (1999)2015
Impact of age on retention in care and viral suppression.
Article in Journal of acquired immune deficiency syndromes (1999), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.
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Who cites it
82 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and factors associated with viral non-suppression in people living with HIV receiving antiretroviral therapy in sub-Saharan Africa: A systematic review and meta-analysis.Reviews in medical virology · 2024Pooled it
- Precision medicine evaluation of heterogeneity of treatment effect for a time-to-event outcome with application in a trial of Initial treatment for people living with HIV.Clinical trials (London, England) · 2025Trial
- HIV Social-network intervention more effective in older populations in Kenya.BMC public health · 2024Trial
- Predictors of Treatment Adherence and Virological Failure Among People Living with HIV Receiving Antiretroviral Therapy in a South African Rural Community: A Sub-study of the ITREMA Randomised Clinical Trial.AIDS and behavior · 2023Trial
- Suitability and Acceptability of Decentralised Care for People Living with HIV.AIDS and behavior · 2026Article
- Exploring Intersectionality Among Latinos Living with HIV: A CHAID Analysis of Health Outcomes and Care Engagement.Journal of racial and ethnic health disparities · 2026Article
- Article
- Age and Race Disparities in Viral Suppression and the Moderating Effect of Substance Use Among Men Who Have Sex with Men Living with HIV.The journal of behavioral health services & research · 2026Article
- Poverty and protection: the relationship between multidimensional poverty, social protection interventions, and HIV viral load.AIDS (London, England) · 2025Article
- Retention in HIV Care Still Matters: A Longitudinal Multisite Analysis.Journal of acquired immune deficiency syndromes (1999) · 2025Article
- Article
- Geosocial-networking App Use Among Men who Have Sex with Men in High HIV Community Viral Load Areas of Baltimore City.AIDS and behavior · 2025Article
- Transitions through the HIV continuum of care in people enrolling in care with advanced HIV disease in Latin America.IJID regions · 2025Article
- Evaluation of viral suppression and medication-related burden among HIV-infected adults in a secondary care facility.Exploratory research in clinical and social pharmacy · 2024Article
- Article
- Improving access to HIV care among people who inject drugs through tele-harm reduction: a qualitative analysis of perceived discrimination and stigma.Harm reduction journal · 2024Article
- Temporal dynamics and drivers of durable HIV viral load suppression and persistent high- and low-level viraemia during Universal Test and Treat scale-up in Uganda: a population-based study.Journal of the International AIDS Society · 2024Article
- Correlates of viral suppression among sexual minority men and transgender women living with HIV in Mpumalanga, South Africa.PLOS global public health · 2024Article
- Examining the Association Between a Modified Quan-Charlson Comorbidity Index and HIV Viral Suppression: A Cross-Sectional Analysis of DC Cohort Participants.AIDS research and human retroviruses · 2023Article
- Observational
22 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
24 authors.
Funding
Abstract
backgroundRetention in care is important for all HIV-infected persons and is strongly associated with initiation of antiretroviral therapy and viral suppression. However, it is unclear how retention in care and age interact to affect viral suppression. We evaluated whether the association between retention and viral suppression differed by age at entry into care.
methodsCross-sectional analysis (2006-2010) involving 17,044 HIV-infected adults in 14 clinical cohorts across the United States and Canada. Patients contributed 1 year of data during their first full-calendar year of clinical observation. Poisson regression examined associations between retention measures [US National HIV/AIDS Strategy (NHAS), US Department of Health and Human Services (DHHS), 6-month gap, and 3-month visit constancy] and viral suppression (HIV RNA ≤200 copies/mL) by age group: 18-29 years, 30-39 years, 40-49 years, 50-59 years, and 60 years or older.
resultsOverall, 89% of patients were retained in care using the NHAS measure, 74% with the DHHS indicator, 85% did not have a 6-month gap, and 62% had visits in 3-4 quarters of the year; 54% achieved viral suppression. For each retention measure, the association with viral suppression was significant for only the younger age groups (18-29 and 30-39 years): 18-29 years [adjusted prevalence ratio (APR) = 1.33, 95% confidence interval (CI): 1.03 to 1.70]; 30-39 years (APR = 1.23, 95% CI: 1.01 to 1.49); 40-49 years (APR = 1.06, 95% CI: 0.90 to 1.22); 50-59 (APR = 0.92, 95% CI: 0.75 to 1.13); ≥60 years (APR = 0.99, 95% CI: 0.63 to 1.56) using the NHAS measure as a representative example.
conclusionsThese results have important implications for improving viral control among younger adults, emphasizing the crucial role retention in care plays in supporting viral suppression in this population.
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