Evidence map›Paper›PMID 25559590›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2015

Effect of pregnancy and the postpartum period on adherence to antiretroviral therapy among HIV-infected women established on treatment.

Cassidy E Henegar, Daniel J Westreich, Mhairi Maskew, William C Miller, M Alan Brookhart, Annelies Van Rie

Open access · greenAbstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Cassidy E Henegar*Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC; †Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; and ‡Division of Infectious Diseases, Department of Medicine, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
Daniel J Westreich
Mhairi Maskew
William C Miller
M Alan Brookhart
Annelies Van Rie
University of North Carolina at Chapel Hill · USUniversity of the Witwatersrand · ZA

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Pregnancy and Response to Antiretroviral Therapy in South AfricaR00HD063961 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WESTREICH, DANIEL J · 2010 to 2012
$687k
NIAID NIH HHS P30 AI050410NICHD NIH HHS R00 HD063961NICHD NIH HHS R00-HD-06-3961PEPFAR
6 · The paper itself

Abstract

: Among women who become pregnant after initiating highly active antiretroviral therapy (HAART), few data describe the effect of pregnancy and postpartum on adherence. We conducted a retrospective clinical cohort study among therapy-naive women (age, 18-45 years) initiating HAART in Johannesburg, South Africa. Among 7510 women in our analysis, 896 experienced a pregnancy after starting HAART. Compared with nonpregnant periods of follow-up, there was an increased risk of nonadherence during the postpartum period (weighted risk ratio: 1.46, 95% confidence interval: 1.17 to 1.82) but not during pregnancy itself (weighted risk ratio: 0.95, 95% confidence interval: 0.78 to 1.17).

Indexed as

Medication AdherencePostpartum PeriodPregnancy Complications, InfectiousAdolescentAdultAntiretroviral Therapy, Highly ActiveCohort StudiesFemaleHIV InfectionsHumansMiddle AgedPregnancyRetrospective StudiesSouth AfricaYoung Adult

Identifiers

PMID25559590
PMCPMC4374144
OpenAlexW1974757616

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.